Dose-volunle characteristics of a 50-kV electronic brachytherapy source for intracavitary accelerated partial breast irradiation

被引:15
作者
Smitt, Melanie C. [1 ]
Kirby, Rob [2 ]
机构
[1] Stanford Univ, Dept Radiat Oncol, Stanford, CA 94305 USA
[2] Xoft Inc, Fremont, CA USA
关键词
breast cancer; brachytherapy; partial breast irradiation;
D O I
10.1016/j.brachy.2007.03.002
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
PURPOSE: To describe dose-voluine data from a 50-kV electronic brachytherapy source in intracavitary accelerated partial breast irradiation. METHODS AND MATERIALS: Three spherical balloon applicators were imaged on a CT scanner in a water phantom and inflated throughout their suggested fill volume range. The planning target volume (PTV) was defined as a 1-cm margin around the balloon surface. Plans were created achieving 80%, 85%, and 90% coverage of the PTV, with a prescription dose of 34 Gy in 10 fractions. The PTV, V-90, V-100, V-150, V-200, and V-300 were recorded for each plan. RESULTS: For 80% target coverage, the V-200 varies from 11 to 14 cm(3) and the V-150 from 26 to 49 cm(3) over all the balloon applicators and fill volumes. For 85%, coverage, the V-200 varies from 14 to 18 cm(3) and the V-150 from 27 to 53 cm(3). For 90% coverage, the V-200 varies from 16 to 22 cm(3) and the V-150 cm(3) from 30 to 61 cm(3). CONCLUSIONS: Fifty-kilovolt electronic brachytherapy can provide PTV coverage similar to (192) Ir in the setting of intracavitary accelerated partial breast irradiation. (C) 2007 American Brachytherapy Society. All rights reserved.
引用
收藏
页码:207 / 211
页数:5
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