High prevalence of hypertension in normal and underweight Indian children

被引:29
作者
Genovesi, Simonetta [1 ,2 ]
Antolini, Laura [3 ]
Gallieni, Maurizio [4 ]
Aiello, Angela [1 ,2 ]
Mandal, Sujit K. Brahmochary [5 ]
Doneda, Anna [6 ]
Giussani, Marco [1 ]
Stella, Andrea [1 ,2 ]
Tucci, Benedetta [1 ,2 ]
Valsecchi, Maria Grazia [3 ]
机构
[1] Univ Milano Bicocca, Dept Clin Med & Prevent, Monza, Italy
[2] San Gerardo Hosp, Nephrol Unit, Monza, Italy
[3] Univ Milano Bicocca, Stat Unit, Dept Clin Med & Prevent, Milan, Italy
[4] Osped San Carlo Borromeo Milano, Nephrol & Dialysis Unit, Milan, Italy
[5] Inst Indian Mother & Child, Kolkata, India
[6] Project People, Milan, Italy
关键词
albuminuria; blood pressure; children; hypertension; pediatric nephrology; SCHOOL-AGED CHILDREN; BLOOD-PRESSURE; ADULT HYPERTENSION; INTERNATIONAL SURVEY; INSULIN-RESISTANCE; OBESITY; OVERWEIGHT; PROTEINURIA; ADOLESCENTS; CHILDHOOD;
D O I
10.1097/HJH.0b013e3283407fe3
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
Background Childhood hypertension is an established predictor of adult hypertension and organ damage, an underestimated problem in developing countries. The aim of the study was to assess the prevalence of arterial hypertension, as well as the relationship of blood pressure values and weight class and urinary abnormalities in 1176 children (aged 5-12 years) from a suburban area south of Kolkata, India. Method Arterial blood pressure, height, weight and waist circumference were measured. Weight class was defined according to the tables of the International Obesity Task Force. Urinalysis was performed with reagent strips to detect glucosuria, microhematuria and proteinuria. Results The majority of children (74.7%) were underweight and 5.2% had systolic and/or diastolic blood pressure values higher or equal to the 95th percentile, according to the National High Blood Pressure Education Program normograms. Hypertension had a high prevalence both in underweight children (4.3%) and in normal-weight children (6.9%) and significantly increased in the rare overweight children (4/20, 20%). A fraction of 8.5% of hypertensive children had urinary abnormalities (microhematuria only) vs. 12.5% in nonhypertensive children (P value 0.36). Conclusion Prevalence of hypertension in North-Eastern Indian children is higher than in Western countries and only partly associated to weight class. Causes of hypertension do not seem to be related to overt kidney disease and remain to be elucidated. J Hypertens 29: 217-221 (c) 2011 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.
引用
收藏
页码:217 / 221
页数:5
相关论文
共 33 条
  • [1] [Anonymous], 2008, LANCET, V372, P1708, DOI [10.1016/S0140-6736(08)61713-4, 10.1542/peds.2008-0214]
  • [2] [Anonymous], GLOB STRAT DIET PHYS
  • [3] Screening for urinary abnormalities: worth doing and worth doing well
    Arant, BS
    [J]. LANCET, 1998, 351 (9099) : 307 - 308
  • [4] The developmental origins of insulin resistance
    Barker, DJP
    [J]. HORMONE RESEARCH, 2005, 64 : 2 - 7
  • [5] The role of obesity in the pathogenesis of hypertension
    Bogaert, Yolanda E.
    Linas, Stuart
    [J]. NATURE CLINICAL PRACTICE NEPHROLOGY, 2009, 5 (02): : 101 - 111
  • [6] CONGENITAL OLIGONEPHROPATHY AND THE ETIOLOGY OF ADULT HYPERTENSION AND PROGRESSIVE RENAL INJURY
    BRENNER, BM
    CHERTOW, GM
    [J]. AMERICAN JOURNAL OF KIDNEY DISEASES, 1994, 23 (02) : 171 - 175
  • [7] Brenner BM, 1997, KIDNEY INT, pS124
  • [8] Hypertension and ethnic group
    Brown, MJ
    [J]. BMJ-BRITISH MEDICAL JOURNAL, 2006, 332 (7545): : 833 - 836B
  • [9] Body mass index cut offs to define thinness in children and adolescents: international survey
    Cole, Tim J.
    Flegal, Katherine M.
    Nicholls, Dasha
    Jackson, Alan A.
    [J]. BMJ-BRITISH MEDICAL JOURNAL, 2007, 335 (7612): : 194 - 197
  • [10] Establishing a standard definition for child overweight and obesity worldwide: international survey
    Cole, TJ
    Bellizzi, MC
    Flegal, KM
    Dietz, WH
    [J]. BMJ-BRITISH MEDICAL JOURNAL, 2000, 320 (7244): : 1240 - 1243