Interconvertible Eudesmanolides Containing a 6,12-Hemiketal Function from Salvia castanea DIELS f. tomentosa STIB

被引：10

作者：

Xu, Gang ^{[1
]}

Peng, Li-Yan ^{[1
]}

Shen, Xiao-Ling ^{[2
]}

Zhao, Qin-Shi ^{[1
]}

机构：

[1] Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China

[2] Guangzhou Univ Chinese Med, Inst Trop Med, Guangzhou 510405, Guangdong, Peoples R China

来源：

HELVETICA CHIMICA ACTA | 2010年 / 93卷 / 09期

关键词：

SESQUITERPENOIDS; PALAEFOLIA;

D O I：

10.1002/hlca.200900453

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Two new eudesmanolide sesquiterpenoids containing a hemiacetal function, castanins G and H (1 and 2), were obtained as a pair of interconvertible isomers from the aerial parts of Salvia castanea DIELS f. tomentosa STIB. and separated as their uninterconvertible acetates 3 and 4. Their structures were elucidated by unequivocal interpretation and comparative analysis of the NMR and MS data of the mixture 1/2 and of their acetates 3 and 4. respectively. The inhibitory activity of 3 and 4 toward MCF-7. HeLa, and HepG2 cell lines was also evaluated.

引用

页码：1773 / 1778

页数：6

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