Emerging role of calprotectin in gastroenterology

被引:103
作者
Poullis, A
Foster, R
Mendall, MA
Fagerhol, MK
机构
[1] St George Hosp, Sch Med, Gastroenterol Endocrinol & Metab Div, London SW17 0RE, England
[2] Mayday Univ Hosp, Surrey, England
[3] Ullevaal Univ Hosp, Dept Immunol & Transfus Med, Oslo, Norway
关键词
biological marker; calprotectin; gastroenterology;
D O I
10.1046/j.1440-1746.2003.03014.x
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Calprotectin is a calcium and zinc binding protein of the S100 family derived predominantly from neutrophils and monocytes. It is detectable in body fluids and tissue samples and is emerging as a valuable marker in the diagnosis, and the monitoring and determining of the prognosis of commonly encountered gastroenterological conditions. Fecal calprotectin, in particular, has for a long time been regarded as a promising marker of gastrointestinal pathology and has now been established as a routine test in Norway and at several centers in the UK. (C) 2003 Blackwell Publishing Asia Pty Ltd.
引用
收藏
页码:756 / 762
页数:7
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