Mucosal immunity and vaccines

被引：1163
作者：
Holmgren, J [1 ]
Czerkinsky, C
机构：
[1] Univ Gothenburg, Dept Med Microbiol & Immunol, SE-40530 Gothenburg, Sweden
[2] Univ Gothenburg, Goteborg Univ Vaccine Res Inst GUVAX, SE-40530 Gothenburg, Sweden
[3] Fac Med Pasteur, INSERM, Unite 721, F-06107 Nice, France
来源：
NATURE MEDICINE | 2005年 / 11卷 / 04期
关键词：
D O I：
10.1038/nm1213
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
There is currently great interest in developing mucosal vaccines against a variety of microbial pathogens. Mucosally induced tolerance also seems to be a promising form of immunomodulation for treating certain autoimmune diseases and allergies. Here we review the properties of the mucosal immune system and discuss advances in the development of mucosal vaccines for protection against infections and for treatment of various inflammatory disorders.
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收藏
页码：S45 / S53
页数：9
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