The antibacterial potency of the medicinal maggot, Lucilia sericata (Meigen): Variation in laboratory evaluation

被引:25
作者
Barnes, Katherine M. [1 ]
Dixon, Ronald A. [1 ]
Gennard, Dorothy E. [1 ]
机构
[1] Lincoln Univ, Sch Nat & Appl Sci, Brayford Pool LN6 7TS, Lincoln, England
关键词
Antibacterial; Insects; Maggot debridement therapy; Wounds; STAPHYLOCOCCUS-AUREUS; BACTERIA; EXCRETIONS/SECRETIONS; DESTRUCTION; CALLIPHORIDAE; SECRETIONS; BIOFILMS; DIPTERA; TRACT; MRSA;
D O I
10.1016/j.mimet.2010.06.005
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Research to quantify the potency of larval excretion/secretion from Lucilia sericata using liquid culture assays has produced contradictory results. In this study, viable counting was used to investigate the effectiveness of excretion/secretion against three marker bacterial species (Pseudomonas aeruginosa, Staphylococcus aureus, and Escherichia coli) and the effects of varying growing conditions in assays. Results demonstrate that factors such as number of larvae, species of bacteria and addition of nutrient influence its antibacterial potency. Therefore a standardised method should be employed for liquid culture assays when investigating the antibacterial activity of larval excretion/secretion from L sericata. (C) 2010 Elsevier B.V. All rights reserved.
引用
收藏
页码:234 / 237
页数:4
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