Colorectal cancer screening: Prospects for molecular stool analysis

被引：169
作者：
Davies, RJ
Miller, R
Coleman, N
机构：
[1] MRC, Hutchison MRC Res Ctr, Canc Cell Unit, Cambridge CB2 2XZ, England
[2] Addenbrookes Hosp, Dept Gen Surg, Cambridge CB2 2QQ, England
来源：
NATURE REVIEWS CANCER | 2005年 / 5卷 / 03期
关键词：
D O I：
10.1038/nrc1569
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Colorectal cancer is common. As many patients present with advanced disease, an effective screening test would have substantial clinical benefits. Recent progress in understanding the biology of colorectal cancer ( and of cancer cells in general) has led to possible new approaches to screening. In particular, there are prospects of developing tests based on analysis of stool, which promise improved accuracy, safety, affordability and patient compliance.
引用
收藏
页码：199 / 209
页数：11
相关论文
共 108 条
  • [11] Translational approaches to improving cervical screening
    Baldwin, P
    Laskey, R
    Coleman, N
    [J]. NATURE REVIEWS CANCER, 2003, 3 (03) : 217 - 226
  • [12] Isolation of exfoliated colonocytes from human stool as a new technique for colonic cytology
    Bandaletova, T
    Bailey, N
    Bingham, SA
    Loktionov, A
    [J]. APMIS, 2002, 110 (03) : 239 - 246
  • [13] BEDI A, 1995, CANCER RES, V55, P1811
  • [14] Boland CR, 2000, ANN NY ACAD SCI, V910, P50
  • [15] DNA integrity as a potential marker for stool-based detection of colorectal cancer
    Boynton, KA
    Summerhayes, IC
    Ahlquist, DA
    Shuber, AP
    [J]. CLINICAL CHEMISTRY, 2003, 49 (07) : 1058 - 1065
  • [16] Reproducibility of a multitarget stool-based DNA assay for colorectal cancer detection
    Brand, RE
    Ross, ME
    Shuber, AP
    [J]. AMERICAN JOURNAL OF GASTROENTEROLOGY, 2004, 99 (07) : 1338 - 1341
  • [17] DNA MISMATCH REPAIR AND CANCER
    CHUNG, DC
    RUSTGI, AK
    [J]. GASTROENTEROLOGY, 1995, 109 (05) : 1685 - 1699
  • [18] Efficacy in standard clinical practice of colonoscopic polypectomy in reducing colorectal cancer incidence
    Citarda, F
    Tomaselli, G
    Capocaccia, R
    Barcherini, S
    Crespi, M
    [J]. GUT, 2001, 48 (06) : 812 - 815
  • [19] Perforated colon secondary to virtual colonoscopy: Report of a case
    Coady-Fariborzian, L
    Angel, LP
    Procaccino, JA
    [J]. DISEASES OF THE COLON & RECTUM, 2004, 47 (07) : 1247 - 1249
  • [20] A randomised trial of the impact of new faecal haemoglobin test technologies on population participation in screening for colorectal cancer
    Cole, SR
    Young, GP
    Esterman, A
    Cadd, B
    Morcom, J
    [J]. JOURNAL OF MEDICAL SCREENING, 2003, 10 (03) : 117 - 122
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