Hypertrophic osteopathy and bone metastases in a dog with prostatic carcinoma

被引:1
作者
Vielmo, Andreia [1 ]
Bianchi, Ronaldo Michel [1 ]
Gomes Kinappe, Leticia Franciele [2 ]
Gomes, Cristiano [2 ]
Pavarini, Saulo Petinatti [1 ]
机构
[1] Univ Fed Rio Grande do Sul UFRGS, Fac Vet, Setor Patol Vet, BR-90040060 Porto Alegre, RS, Brazil
[2] Univ Fed Rio Grande do Sul UFRGS, Dept Med Anim, Fac Vet, Porto Alegre, RS, Brazil
来源
CIENCIA RURAL | 2020年 / 50卷 / 08期
关键词
dog diseases; neoplasia; prostate; pathology; LESIONS; CANCER; RISK;
D O I
10.1590/0103-8478cr20191007
中图分类号
S3 [农学(农艺学)];
学科分类号
0901 ;
摘要
Prostatic carcinomas in are aggressive neoplasms and bone metastases may occur: however, hypertrophic osteopathy associated with that condition is poorly documented. A ten-year-old, neutered male, mixed breed dog had a history of lameness and volume increase in the left pelvic limb. On radiographic examination, a lytic bone mass was observed in the left metatarsus, as well as a diffiise proliferative periosteal reaction in several bones of the appendicular skeleton, in addition to radiopaque nodular structures in all lung lobes. A presumptive diagnosis of primary bone neoplasia with pulmonary metastases and hypertrophic osteopathy was established and chemotherapy treatment was started. However, there was no satisfactory clinical response, and euthanasia was ellected. At necropsy, there was moderate enlargement of the prostate gland. The gland was firm and whitish, with a multilobulated aspect. Several similar masses were observed in the right kidney, lungs, mediastinal lymph nodes, and multiple bones of the appendicular skeleton. These bones also presented evident diffuse periosteal reaction. Histological examination revealed a metastatic prostatic carcinoma with bone involvement and hypertrophic osteopathy. This report is an unusual case of metastatic prostatic carcinoma in association with hypertrophic osteopathy and concomitant bone metastases.
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共 18 条
[1]   Prognostic factors in canine appendicular osteosarcoma - a meta-analysis [J].
Boerman, Ilse ;
Selvarajah, Gayathri T. ;
Nielen, Mirjam ;
Kirpensteijn, Jolle .
BMC VETERINARY RESEARCH, 2012, 8
[2]   A population study of neutering status as a risk factor for canine prostate cancer [J].
Bryan, Jeffrey N. ;
Keeler, Matthew R. ;
Henry, Carolyn J. ;
Bryan, Margaret E. ;
Hahn, Allen W. ;
Caldwell, Charles W. .
PROSTATE, 2007, 67 (11) :1174-1181
[3]   Hypertrophic osteopathy in a dog associated with intra-thoracic lesions: a case report and a review [J].
Cetinkaya, M. A. ;
Yardimci, B. ;
Yardimci, C. .
VETERINARNI MEDICINA, 2011, 56 (12) :595-601
[4]   Canine Prostate Disease [J].
Christensen, Bruce W. .
VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE, 2018, 48 (04) :701-+
[5]   Skeletal metastasis as the initial clinical manifestation of metastatic carcinoma in 19 dogs [J].
Cooley, DM ;
Waters, DJ .
JOURNAL OF VETERINARY INTERNAL MEDICINE, 1998, 12 (04) :288-293
[6]  
Cornell KK, 2000, PROSTATE, V45, P173
[7]  
Craig LE, 2016, Jubb, Kennedy and Palmer's Pathology of Domestic Animals, V6th, P17
[8]   Estrogen-dependent induction of cyclooxygenase-2 in the canine prostate in vivo [J].
Doré, M ;
Chevalier, S ;
Sirois, J .
VETERINARY PATHOLOGY, 2005, 42 (01) :100-103
[9]   Hypertrophic osteopathy in a castrated dog with prostatic carcinoma and prostatitis [J].
Jennings, K. ;
Watts, J. .
JOURNAL OF SMALL ANIMAL PRACTICE, 2018, 59 (11) :719-719
[10]   Prostatic disorders in the dog [J].
Johnston, SD ;
Kamolpatana, K ;
Root-Kustritz, MV ;
Johnston, GR .
ANIMAL REPRODUCTION SCIENCE, 2000, 60 :405-415