Use of inotropes and vasopressor agents in critically ill patients

被引：119

作者：

Bangash, Mansoor N. ^{[1
]}

Kong, Ming-Li ^{[1
]}

Pearse, Rupert M. ^{[1
]}

机构：

[1] Barts & London Queen Marys Sch Med & Dent, William Harvey Res Inst, London, England

来源：

BRITISH JOURNAL OF PHARMACOLOGY | 2012年 / 165卷 / 07期

关键词：

inotrope; vasopressor; critical illness; haemodynamic shock; CONTRAST-INDUCED NEPHROPATHY; PULMONARY-ARTERY CATHETERS; ORIENTED HEMODYNAMIC THERAPY; MAXIMIZING OXYGEN DELIVERY; BETA-ADRENERGIC RECEPTORS; STANDARD-DOSE EPINEPHRINE; RANDOMIZED CLINICAL-TRIAL; GOAL-DIRECTED THERAPY; TUMOR-NECROSIS-FACTOR; REGIONAL BLOOD-FLOW;

D O I：

10.1111/j.1476-5381.2011.01588.x

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Inotropes and vasopressors are biologically and clinically important compounds that originate from different pharmacological groups and act at some of the most fundamental receptor and signal transduction systems in the body. More than 20 such agents are in common clinical use, yet few reviews of their pharmacology exist outside of physiology and pharmacology textbooks. Despite widespread use in critically ill patients, understanding of the clinical effects of these drugs in pathological states is poor. The purpose of this article is to describe the pharmacology and clinical applications of inotropic and vasopressor agents in critically ill patients.

引用

页码：2015 / 2033

页数：19

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