Iridium-Catalyzed Enantioselective Hydrogenation of Alkenylboronic Esters

被引：47
作者：
Ganic, Adnan [1 ]
Pfaltz, Andreas [1 ]
机构：
[1] Univ Basel, Dept Chem, CH-4056 Basel, Switzerland
来源：
CHEMISTRY-A EUROPEAN JOURNAL | 2012年 / 18卷 / 22期
基金：
瑞士国家科学基金会;
关键词：
asymmetric catalysis; boron; hydrogenation; iridium; N; P ligands; ASYMMETRIC HYDROGENATION; BORONIC ESTERS; BIPI LIGANDS; HYDROBORATION; OLEFINS; ALKENES; HOMOLOGATION; DERIVATIVES; DIBORON; DIBORATION;
D O I：
10.1002/chem.201200246
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Choose the right ligand: An iridium complex derived from a phosphino-imidazoline ligand is a highly efficient catalyst for the asymmetric hydrogenation of terminal vinyl boronic esters (see scheme). On the other hand, trisubstituted alkenyl-boronates can be reduced with high activity and good to excellent enantioselectivity employing a pyridine-phosphinite ligand. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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收藏
页码：6724 / 6728
页数：5
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