PELDOR study on the tyrosyl radicals in the R2 protein of mouse ribonucleotide reductase

被引：19

作者：

Biglino, D ^{[1
]}

Schmidt, PP ^{[1
]}

Reijerse, EJ ^{[1
]}

Lubitz, W ^{[1
]}

机构：

[1] Max Planck Inst Bioinorgan Chem, D-45470 Mulheim, Germany

来源：

PHYSICAL CHEMISTRY CHEMICAL PHYSICS | 2006年 / 8卷 / 01期

关键词：

D O I：

10.1039/b513950c

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Pulse electron - electron double resonance (PELDOR) has been employed to measure the distance between the putative tyrosyl radicals in the two halves of the R2 subunit from mouse ribonucleotide reductase. The results provide experimental evidence that the active, tyrosyl radical containing mouse R2 subunit forms a homodimeric form in solution. The distance between the two tyrosyl radicals present in the dimer was determined to be 3.25 +/- 0.05 nm.

引用

页码：58 / 62

页数：5

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