Single Molecules, Cells, and Super-Resolution Optics (Nobel Lecture)

被引：133

作者：

Betzig, Eric ^{[1
]}

机构：

[1] Howard Hughes Med Inst, Ashburn, VA 20147 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2015年 / 54卷 / 28期

关键词：

microscopy; near-field; PALM; super-resolution; GREEN FLUORESCENT PROTEIN; PHOTOACTIVATED LOCALIZATION MICROSCOPY; STRUCTURED-ILLUMINATION MICROSCOPY; NEAR-FIELD SPECTROSCOPY; ELECTRON-MICROSCOPY; DIFFRACTION LIMIT; RESOLUTION; EXCITATION; DYNAMICS; BLINKING;

D O I：

10.1002/anie.201501003

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The resolution of a microscope is determined by the diffraction limit in classical microscopy, whereby objects that are separated by half a wavelength can no longer be visually separated. To go below the diffraction limit required several tricks and discoveries. In his Nobel Lecture, E. Betzig describes the developments that have led to modern super high-resolution microscopy. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：8034 / 8053

页数：20

共 63 条

[1] SUPER-RESOLUTION APERTURE SCANNING MICROSCOPE [J].