Two new triterpenoid glycosides isolated from Aesculus assamica GRIFF

被引：9
作者：
Liu, HW [1 ]
Zhang, X
Gao, H
Wang, NL
Jin, SL
Cai, B
Yao, XS
Cai, GP
机构：
[1] Natl Tsing Hua Univ, Life Sci Div, Grad Sch Shenzhen, Shenzhen 518055, Peoples R China
[2] Shenzhen Res Ctr Tradit Chinese Med & Nat Prod, Shenzhen 518055, Peoples R China
[3] Tianjin Inst Biomed, Lab Bioact Assay, Tianjin 300384, Peoples R China
[4] Shenyang Pharmaceut Univ, Dept Nat Prod Chem, Shenyang 110016, Peoples R China
来源：
CHEMICAL & PHARMACEUTICAL BULLETIN | 2005年 / 53卷 / 10期
关键词：
triterpenoid glycoside; Aesculus assamica; anti-fungal activity; cytotoxicity;
D O I：
10.1248/cpb.53.1310
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Phytochemical study of the ethanol extract of the seeds of Aesculus assamica led to the isolation of two new triterpenoid saponins. The structure of the new compounds were elucidated on the basis of spectral data to be 28-O-acetyl-21-O-(4-O-angeloyl)-6-deoxy-beta-glucopyranosyl-3-O-[beta-glueopyranosyl(1-2)-O-[beta-glucopyranosyl(1-4)]-beta-glucuronopyranosyl]protoaeseigenin (1), and 21-O-(4-O-angeloyl)-6-deoxy-beta-glueopyranosyl-3-O-[beta-glueopyranosyl(1-2)-O-[beta-glucopyranosyl(1-4)]-beta-glueuronopyranosyl]protoaescigenin (2). Their in vitro bioactivity against plant pathogenic fungus Pyricularia oryzae and cytotoxicity against K562 and HCT-15 cell lines were evaluated.
引用
收藏
页码：1310 / 1313
页数：4
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