Risk-adapted therapy in acute myeloid leukemia

被引:0
作者
Fiegl, M. [1 ]
Hiddemann, W. [1 ]
机构
[1] Klinikum Ludwig Maximilians Univ Munchen, Med Klin & Poliklin 3, D-81377 Munich, Germany
来源
INTERNIST | 2012年 / 53卷 / 04期
关键词
Leukemia; myeloid; acute; Risk stratification; Induction chemotherapy; Consolidation chemotherapy; Stem cell transplantation; allogeneic; STEM-CELL TRANSPLANTATION; AML-COOPERATIVE-GROUP; HIGH-DOSE CYTARABINE; MINIMAL RESIDUAL DISEASE; PROLONGED MAINTENANCE; COMPLETE REMISSION; INDUCTION THERAPY; PROGNOSTIC-FACTOR; ADULTS; TRIAL;
D O I
10.1007/s00108-011-2986-1
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The identification and characterization of an increasing number of chromosomal and molecular aberrations has not only increased the understanding of the pathogenesis of acute myeloid leukemia but also provides the means for a better judgment of prognosis and the direction of therapy. Together with patient-specific factors like age, co-morbidity, and performance status, an individualized risk profile can be used to select the most appropriate therapeutic strategy.
引用
收藏
页码:392 / +
页数:7
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