Systemic approach to improving treatment outcome in nasopharyngeal carcinoma: Current and future directions

被引：110

作者：

Ma, Brigette B. Y. ^{[1
,2
]}

Hui, Edwin P. ^{[1
,2
]}

Chan, Anthony T. C. ^{[1
,2
]}

机构：

[1] Prince Wales Hosp, Sir YK Pao Ctr Canc, Dept Clin Oncol, Hong Kong, Peoples R China

[2] Chinese Univ Hong Kong, State Key Lab Oncol S China, Hong Kong, Peoples R China

来源：

CANCER SCIENCE | 2008年 / 99卷 / 07期

关键词：

D O I：

10.1111/j.1349-7006.2008.00836.x

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Systemic therapy is an integral part of the management of non-keratinizing nasopharyngeal carcinoma (NPC). The purposes of this review are to provide the latest results and future directions of clinical and translational research for this disease, and to illustrate how some of these new therapies have improved the treatment outcome for patients with NPC. Particular attention will be paid to the clinical application of chemotherapy in the adjunctive treatment of locoregionally advanced NPC, novel targeted drugs, Epstein-Barr virus-targeted vaccine therapies, and the use of plasma Epstein-Barr virus DNA as a biomarker for selecting patients for adjunctive therapies.

引用

页码：1311 / 1318

页数：8

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