Fatigue and apathy in patients on chronic hemodialysis

被引：6
作者：
Bossola, Maurizio [1 ,2 ]
Di Stasio, Enrico [2 ,3 ]
Monteburini, Tania [4 ]
Santarelli, Stefano [4 ]
Cenerelli, Stefano [5 ]
Manes, Massimo [6 ]
Parodi, Emanuele Luigi [6 ]
Angioletti, Laura [7 ,8 ]
Balconi, Michela [7 ,8 ]
机构：
[1] Univ Cattolica Sacro Cuore, Serv Emodialisi, Rome, Italy
[2] Fdn Policlin Univ A Gemelli IRCCS, Rome, Italy
[3] Univ Cattolica Sacro Cuore, Dipartimento Sci Biotecnol Base Clin Intensivol &, Rome, Italy
[4] Osped Carlo Urbani, Dipartimento Nefrol, Jesi, Italy
[5] Osped Chile, Dipartimento Nefrol, Senigallia, Italy
[6] Osped Umberto Parini, Dipartimento Nefrol, Aosta, Italy
[7] Univ Cattolica Sacro Cuore, Int Res Ctr Cognit Appl Neurosci IrcCAN, Milan, Italy
[8] Univ Cattolica Sacro Cuore, Res Unit Affect & Social Neurosci, Dipartimento Psicol, Milan, Italy
来源：
THERAPEUTIC APHERESIS AND DIALYSIS | 2022年 / 26卷 / 05期
关键词：
apathy; depression; end-stage renal disease; fatigue; hemodialysis; PARKINSONS-DISEASE; POSTDIALYSIS FATIGUE; DEPRESSION; PREVALENCE; INFLAMMATION; ASSOCIATION; VALIDITY; OUTCOMES; SLEEP; SCALE;
D O I：
10.1111/1744-9987.13784
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Introduction This study explores the link between fatigue and apathy in patients on chronic hemodialysis (HD). Methods One hundred thirty-nine chronic HD patients underwent the assessment of fatigue, apathy, depression, and their functional status, with the fatigue severity scale (FSS), the Apathy Evaluation Scale (AES), the beck depression inventory (BDI), the activity of daily living (ADL), and instrumental activity of daily living (IADL). Results Patients with high FSS had a significantly lower ADL and IADL score, higher BDI, Charlson Comorbidity Index, and AES score, and lower serum levels of creatinine, compared to low FSS patients. FSS was highly correlated with the AES, as well as with the BDI and the AES correlates with the BDI. At multiple regression analyses, only apathy and IADL were independent predictor variables of fatigue in HD population. Conclusion Future longitudinal studies could determine if apathy is a causative factor for fatigue manifestation and development in HD patients.
引用
收藏
页码：932 / 940
页数：9
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