Long-term survival of the very elderly undergoing coronary artery bypass grafting

被引:78
|
作者
Likosky, Donald S.
Dacey, Lawrence J.
Baribeau, Yvon R.
Leavitt, Bruce J.
Clough, Robert
Cochran, Richard P.
Quinn, Reed
Sisto, Donato A.
Charlesworth, David C.
Malenka, David J.
MacKenzie, Todd A.
Olmstead, Elaine M.
Ross, Cathy S.
O'Connor, Gerald T.
机构
[1] Dartmouth Coll, Hitchcock Med Ctr, Dartmouth Med Sch, Dept Surg, Hanover, NH 03756 USA
[2] Dartmouth Coll, Hitchcock Med Ctr, Dartmouth Med Sch, Dept Community & Family Med, Hanover, NH 03756 USA
[3] Dartmouth Coll, Hitchcock Med Ctr, Dartmouth Med Sch, Dartmouth Inst Hlth Policy & Clin Practice, Hanover, NH 03756 USA
[4] Dartmouth Hitchcock Med Ctr, Hanover, NH USA
[5] Catholic Med Ctr, Manchester, NH USA
[6] Fletcher Allen Hlth Care, Burlington, VT USA
[7] Eastern Maine Med Ctr, Bangor, ME USA
[8] Cent Maine Med Ctr, Lewiston, ME USA
[9] Maine Med Ctr, Portland, ME 04102 USA
[10] Portsmouth Reg Hosp, Portsmouth, NH USA
来源
ANNALS OF THORACIC SURGERY | 2008年 / 85卷 / 04期
关键词
D O I
10.1016/j.athoracsur.2007.12.066
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background. Increasing numbers of the very elderly are undergoing coronary artery bypass graft surgery (CABG). Short-term results have been studied, but few data are available concerning long-term outcomes. Methods. We conducted a cohort study of 54,397 consecutive patients undergoing primary, isolated CABG surgery between July 1, 1987, and June 30, 2006. Patient records were linked to the Social Security Administration's Death Master File. Results. During 390,871 person-years of follow-up, there were 17,352 deaths. There were 51,149 patients younger than 80 years, 2,661 patients aged 80 to 84 years, and 587 patients aged 85 or more years who underwent isolated CABG surgery. Crude in-hospital survival was 97.2% for those less than 80 years, 98.3% for those aged 80 to 84 years, and 87.6% for those aged 85 or more years. Patients aged 80 or more years were more likely to female (46.9%), more likely to be emergency priority (10.2%), and more likely to have associated comorbidities than younger patients. Patients aged 85 or more years were more likely to have intraoperative and postoperative morbid events. Among patients younger than 80, median survival was 14.4 years with an annual incidence of death of 4.2%. Among patients 80 to 84 years old, median survival time was 7.4 years, with an annual incidence rate of death of 10.3%. Among patients aged 85 or more years, median survival was 5.8 years, and the annual incidence of death was 13.7%. Conclusions. Although very elderly CABG patients have more comorbidities and more acute presentation than younger patients and their in-hospital mortality rate is high, their long-term survival is surprisingly good.
引用
收藏
页码:1233 / 1238
页数:7
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