Design of MDIs for Type 1 Diabetes Treatment via Rolling Horizon Cardinality-Constrained Optimisation

被引：4
作者：
Carrasco, Diego S. [1 ]
Matthews, Aaron D. [1 ]
Goodwin, Graham C. [1 ]
Delgado, Ramon A. [1 ]
Medioli, Adrian M. [1 ]
机构：
[1] Univ Newcastle, Sch Elect Engn & Comp Sci, Callaghan, NSW 2308, Australia
来源：
IFAC PAPERSONLINE | 2017年 / 50卷 / 01期
关键词：
optimisation; diabetes; blood glucose regulation; ARTIFICIAL PANCREAS;
D O I：
10.1016/j.ifacol.2017.08.2516
中图分类号：
TP [自动化技术、计算机技术];
学科分类号：
0812 ;
摘要：
Recent results on cardinality constrained optimisation are used to obtain an optimised Multiple Daily Injection (MDI) insulin regimen for Type 1 Diabetes patients. The optimisation is implemented in a rolling horizon fashion to account for unannounced events. A blood glucose model is described and an algorithm developed to illustrate the aforementioned strategy. The impact of varying the number of allowable injections in a given day is also studied. Real patient data is used to obtain the models and simulation results are included. (C) 2017, IFAC (International Federation of Automatic Control) Hosting by Elsevier Ltd. All rights reserved.
引用
收藏
页码：15044 / 15049
页数：6
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