Metaplastic carcinomas of the breast - fine needle aspiration (FNA) cytology findings

被引:26
作者
Nogueira, M [1 ]
Andre, S [1 ]
Mendonca, E [1 ]
机构
[1] Ctr Lisboa, Inst Portugues Oncol Francisco Gentil, Dept Patol Morfol, P-1093 Lisbon, Portugal
关键词
breast; metaplastic carcinomas; cytologic features;
D O I
10.1046/j.1365-2303.1998.00118.x
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Metaplastic carcinomas of the breast are defined by mesenchymal and/or squamous cell components associated with ductal carcinoma and may raise diagnostic problems in FNA cytology. We reviewed FNA smears of a series of nine cases; seven were compared with histological sections and two with cell-block sections. The cytological pattern was diagnostic of carcinoma in six cases; in two cases a diagnosis of sarcoma/phyllodes tumour was considered, as cells were predominantly spindle-shaped. One case had a pleomorphic adenoma type pattern. The cytological findings suggesting a diagnosis of metaplastic carcinoma include a liquid aspirate, a proteinaceous or chondromyxoid background and a poorly differentiated tumour with multinucleated giant cells, neoplastic or histiocytic. A definite diagnosis requires the presence of both carcinomatous and metaplastic (squamous/mesenchymal) components.
引用
收藏
页码:291 / 300
页数:10
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