Social Risk Factors for Medication Nonadherence: Findings from the CARDIA Study

被引：31

作者：

Oates, Gabriela R. ^{[1
]}

Juarez, Lucia D. ^{[2
]}

Hansen, Barbara ^{[2
]}

Kiefe, Catarina, I ^{[3
]}

Shikany, James M. ^{[2
]}

机构：

[1] Univ Alabama Birmingham, Div Pulm & Sleep Med, Birmingham, AL 35294 USA

[2] Univ Alabama Birmingham, Div Prevent Med, Birmingham, AL USA

[3] Univ Massachusetts, Med Sch, Populat & Quantitat Hlth Sci, Worcester, MA 01605 USA

来源：

AMERICAN JOURNAL OF HEALTH BEHAVIOR | 2020年 / 44卷 / 02期

基金：

美国国家卫生研究院; 美国医疗保健研究与质量局;

关键词：

medication adherence; social factors; income; chronic stress; TREATMENT ADHERENCE; EXERCISE ADHERENCE; PATIENT ADHERENCE; DIABETES PATIENTS; PERCEIVED STRESS; REFILL ADHERENCE; FINANCIAL STRAIN; CHRONIC DISEASES; CHRONIC ILLNESS; LIFE STRESS;

D O I：

10.5993/AJHB.44.2.10

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Objectives: Nonadherence to medications has been documented, but the combined effect of social risk factors on medication nonadherence has not been investigated. Methods: We conducted a cross-sectional analysis of data from the Coronary Artery Risk Development in Young Adults (CARDIA) study, a population-based prospective cohort. The sample (N = 1506) included subjects who at Year 20 (2005-06) were taking prescription medications and completed a 4-item Medication Adherence Scale. Social risk factors were education of high school or less, annual household income <$25,000, high financial strain, high chronic stress, low social support, and high social strain. Results: In a fully adjusted logistic regression model, income <$25,000 (OR = 2.37 [95% CI 1.12-4.98], p < .05) and high chronic stress (OR = 2.07 [95% CI 1.09-3.94], p < .05) were significantly associated with medication nonadherence. Individuals with >= 3 social risk factors had >3 times higher odds of nonadherence than counterparts with no social risk factors (OR = 3.26 [95% CI 1.72-6.19], p < .001). Conclusion: Low income and chronic stress are associated with medication nonadherence, and the odds of nonadherence increase with the accumulation of social risk factors. Findings may be used to develop risk prediction tools to identify individuals who can benefit from adherence-promoting interventions.

引用

页码：232 / 243

页数：12