Applications of Light Emitting Diodes in Health Care

被引:31
作者
Dong, Jianfei [1 ]
Xiong, Daxi [1 ]
机构
[1] Chinese Acad Sci, Suzhou Inst Biomed Engn & Technol, Suzhou, Peoples R China
基金
国家重点研发计划;
关键词
Light-emitting diode; Illumination control; Photobiomodulation; Light therapy; Active vision; Optogenetics; LEVEL LASER THERAPY; GENE-EXPRESSION; DOSE-RESPONSE; ILLUMINATION; MODEL; LEDS; IRRADIATION; CHALLENGES; FEEDBACK; SPECTRA;
D O I
10.1007/s10439-017-1930-5
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Light emitting diodes (LEDs) have become the main light sources for general lighting, due to their high lumen efficiency and long life time. Moreover, their high bandwidth and the availability of diverse wavelength contents ranging from ultraviolet to infrared empower them with great controllability in tuning brightness, pulse durations and spectra. These parameters are the essential ingredients of the applications in medical imaging and therapies. Despite the fast advances in both LED technologies and their applications, few reviews have been seen to link the controllable emission properties of LEDs to these applications. The objective of this paper is to bridge this gap by reviewing the main control techniques of LEDs that enable creating enhanced lighting patterns for imaging and generating effective photon doses for photobiomodulation. This paper also provides the basic mechanisms behind the effective LED therapies in treating cutaneous and neurological diseases. The emerging field of optogenetics is also discussed with a focus on the application of LEDs. The multidisciplinary topics reviewed in this paper can help the researchers in LEDs, imaging, light therapy and optogenetics better understand the basic principles in each other's field; and hence to stimulate the application of LEDs in health care.
引用
收藏
页码:2509 / 2523
页数:15
相关论文
共 103 条
[1]   Combination 830-nm and 633-nm Light-Emitting Diode Phototherapy Shows Promise in the Treatment of Recalcitrant Psoriasis: Preliminary Findings [J].
Ablon, Glynis .
PHOTOMEDICINE AND LASER SURGERY, 2010, 28 (01) :141-146
[2]  
[Anonymous], 2005, P SPIE
[3]   Bisphosphonate-related osteonecrosis: laser-assisted surgical treatment or conventional surgery? [J].
Atalay, Belir ;
Yalcin, Serhat ;
Emes, Yusuf ;
Aktas, Irem ;
Aybar, Buket ;
Issever, Halim ;
Mandel, Nil Molinas ;
Cetin, Ozge ;
Oncu, Bora .
LASERS IN MEDICAL SCIENCE, 2011, 26 (06) :815-823
[4]  
Avci P, 2013, SEMIN CUTAN MED SURG, V32, P41
[5]   Model Predictive Control for Luminous Flux Tracking in Light-Emitting Diodes [J].
Baccari, Silvio ;
Vasca, Francesco ;
Tipaldi, Massimo ;
Iannelli, Luigi .
IEEE TRANSACTIONS ON CONTROL SYSTEMS TECHNOLOGY, 2017, 25 (02) :695-703
[6]   Regulation of Skin Collagen Metabolism In Vitro Using a Pulsed 660 nm LED Light Source: Clinical Correlation with a Single-Blinded Study [J].
Barolet, Daniel ;
Roberge, Charles J. ;
Auger, Francois A. ;
Boucher, Annie ;
Germain, Lucie .
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2009, 129 (12) :2751-2759
[7]   Light-Emitting Diodes (LEDs) in Dermatology [J].
Barolet, Daniel .
SEMINARS IN CUTANEOUS MEDICINE AND SURGERY, 2008, 27 (04) :227-238
[8]   Lambertian reflectance and linear subspaces [J].
Basri, R ;
Jacobs, DW .
IEEE TRANSACTIONS ON PATTERN ANALYSIS AND MACHINE INTELLIGENCE, 2003, 25 (02) :218-233
[9]  
Beckmann K. H., 2014, Evid. Based Complementary Altern. Med, V2014, P1
[10]  
Bender VC, 2012, IEEE IND ELEC, P4545, DOI 10.1109/IECON.2012.6389453