A facile and efficient carbodiimide-mediated synthesis of dihydroquinazolines via a tandem nucleophilic addition-intramolecular hetero conjugate addition annulation strategy

被引：51
作者：
Saito, T
Tsuda, K
Saito, Y
机构：
[1] Department of Chemistry, Faculty of Science, Science University of Tokyo, Tokyo 162, Kagurazaka, Shinjuku-ku
来源：
TETRAHEDRON LETTERS | 1996年 / 37卷 / 02期
关键词：
D O I：
10.1016/0040-4039(95)02130-2
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A novel and efficient method is described for the synthesis of dihydroquinazoline derivatives which involves initial addition of a nucleophile (alcohol, amine and thiol) to the carbodiimide cumulenic system followed by intramolecular hetero conjugate addition annulation.
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收藏
页码：209 / 212
页数：4
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