Surgical management of portal hypertension in children

被引:52
作者
de Goyet, Jean de Ville [1 ]
D'Ambrosio, Giuseppe [1 ]
Grimaldi, Chiara [1 ]
机构
[1] Bambino Gesu Pediat Hosp, Dept Paediat Surg & Transplantat, I-00165 Rome, Italy
关键词
Portal hypertension; Portosystemic shunts; Liver transplantation; Meso-Rex bypass; PARTIAL SPLENIC EMBOLIZATION; ENDOSCOPIC VARICEAL LIGATION; INTRAHEPATIC ARTERIOPORTAL FISTULA; MINIMAL HEPATIC-ENCEPHALOPATHY; BUDD-CHIARI-SYNDROME; FACTOR-V-LEIDEN; VEIN THROMBOSIS; VENOUS OBSTRUCTION; PROTEIN-C; REX SHUNT;
D O I
10.1053/j.sempedsurg.2012.05.005
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
The management of children with portal hypertension has dramatically changed during the past decade, with an improvement in outcome. This has been achieved by improved efficiency of endoscopic variceal control and the success of liver transplantation. Emergency surgical shunt procedures are rarely required, with acute bleeding episodes generally controlled endoscopically or, occasionally in adults, by interventional radiological procedures. Portosystemic shunts may be considered as a bridge to transplant in adults but are rarely used in this context in children. Nontransplant surgery or radiological interventions may still be indicated for noncirrhotic portal hypertension when the primary cause can be cured and to allow normalization of portal pressure before liver parenchyma is damaged by chronic secondary changes in some specific diseases. The meso-Rex bypass shunt is used widely but is limited to those with a favorable anatomy and can even be performed preemptively. Elective portosystemic shunt surgery is reserved for failure to respond to conservative management in the absence of alternative therapies. (C) 2012 Elsevier Inc. All rights reserved.
引用
收藏
页码:219 / 232
页数:14
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