Sleep Disorders in Chronic Liver Disease

被引:38
作者
De Cruz, Sharon [1 ]
Espiritu, Joseph Roland D. [2 ]
Zeidler, Michelle [1 ]
Wang, Tisha S. [1 ]
机构
[1] Univ Calif Los Angeles, David Geffen Sch Med, Div Pulm Crit Care & Sleep Med, Los Angeles, CA 90095 USA
[2] St Louis Univ, Sch Med, Div Pulm Crit Care & Sleep Med, St Louis, MO USA
关键词
sleep apnea; hepatic cirrhosis; electroence phalogram; polysomnogram; circadian rhythm; PRIMARY BILIARY-CIRRHOSIS; SERUM AMINOTRANSFERASE LEVELS; QUALITY-OF-LIFE; EXCESSIVE DAYTIME SLEEPINESS; TREATED WILSONS-DISEASE; CHRONIC HEPATITIS-C; NONALCOHOLIC STEATOHEPATITIS; APNEA SYNDROME; FATTY LIVER; OBESE-PATIENTS;
D O I
10.1055/s-0032-1301732
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Sleep-related complaints and disturbances are increasingly recognized in the setting of chronic liver disease and have recently been shown to be an important prognostic factor in patients with advanced chronic liver disease. This article reviews the literature surrounding sleep disturbances and disorders in a variety of types of chronic liver disease. This includes the association of sleep disturbances with hepatitis C and antiviral therapy, primary biliary cirrhosis, and Wilson disease as well as the circadian rhythm abnormalities present in cirrhosis and hepatic encephalopathy. The association between chronic liver disease, particularly nonalcoholic fatty liver disease, and sleep-disordered breathing is also reviewed in detail.
引用
收藏
页码:26 / 35
页数:10
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