Fever and Reversible Laboratory Abnormalities Associated with Prolonged Use of Piperacillin-Tazobactam in Children

被引：5

作者：

Patel, Aesha ^{[1
]}

Mao, Kuo-Rei ^{[2
]}

McNeil, J. Chase ^{[1
]}

Kaplan, Sheldon L. ^{[1
]}

Vallejo, Jesus G. ^{[1
]}

机构：

[1] Baylor Coll Med, Dept Pediat, Infect Dis Sect, Houston, TX 77030 USA

[2] Texas Childrens Hosp, Dept Pharm, Houston, TX 77030 USA

来源：

PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2015年 / 34卷 / 08期

关键词：

Piperacillin-tazobactam; adverse drug reaction; pediatrics; NEUTROPENIA;

D O I：

10.1097/INF.0000000000000748

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Piperacillin-tazobactam is used frequently in pediatric patients with complicated appendicitis and other intra-abdominal infections. We report 10 pediatric patients who developed a piperacillin-tazobactam-associated adverse reaction characterized by fever, rash, hematologic abnormalities and transaminitis. Physicians should be aware of this entity in patients treated with a prolonged course of piperacillin-tazobactam. Prompt identification can obviate unnecessary diagnostic testing and treatment.

引用

页码：849 / 850

页数：2

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