Effects of Maternal Linseed Oil Supplementation on Metabolic Parameters in Cafeteria Diet-induced Obese Rats

被引:3
作者
Benaissa, Nawel [1 ]
Merzouk, Hafida [1 ]
Merzouk, Sid Ahmed [2 ]
Narce, Michel [3 ]
机构
[1] Univ Abou Bekr Belkaid Tlemcen, Fac Nat & Life Sci, Dept Biol, Lab Physiol & Biochem Nutr,Earth & Univ, Tilimsen 13000, Algeria
[2] Univ Abou Bekr Belkaid Tlemcen, Fac Engn, Dept Tech Sci, Tilimsen 13000, Algeria
[3] Univ Burgundy, Fac Sci, INSERM, UMR 866,Lipids Nutr Canc, F-21000 Dijon, France
关键词
ADIPOSE-TISSUE;
D O I
10.3967/bes2015.041
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Because linseed oil may influence maternal and fetal metabolisms, we investigated its role in the modulation of lipid metabolism in cafeteria diet-induced obese rats and their offspring. Female Wistar rats were fed control or cafeteria food, which were either supplemented or not supplemented with linseed oil (5%) for 1 month before and during gestation. At parturition, serum and tissue lipids and enzyme activities were analyzed. Cafeteria diet induced adverse metabolic alterations in both mothers and offspring. Linseed oil improved metabolic status. In conclusion, linseed oil displayed health benefits by modulating tissue enzyme activities in both obese mothers and their newborns.
引用
收藏
页码:298 / 302
页数:5
相关论文
共 10 条
[1]   Differential effects of dietary oils on plasma lipids, lipid peroxidation and adipose tissue lipoprotein lipase activity in rats [J].
Baba, NH ;
Ghossoub, Z ;
Habbal, Z .
NUTRITION RESEARCH, 2000, 20 (08) :1113-1123
[2]   Altered adipose tissue metabolism in offspring of dietary obese rat dams [J].
Benkalfat, Nassira Batoul ;
Merzouk, Hafida ;
Bouanane, Samira ;
Merzouk, Sid-Ahmed ;
Bellenger, Jerome ;
Gresti, Joseph ;
Tessier, Christian ;
Narce, Michel .
CLINICAL SCIENCE, 2011, 121 (1-2) :19-28
[3]   Hepatic and very low-density lipoprotein fatty acids in obese offspring of overfed dams [J].
Bouanane, Samira ;
Merzouk, Hafida ;
Benkalfat, Nacira Batoul ;
Soulimane, Nassima ;
Merzouk, Sid Ahmed ;
Gresti, Joseph ;
Tessier, Christian ;
Narce, Michel .
METABOLISM-CLINICAL AND EXPERIMENTAL, 2010, 59 (12) :1701-1709
[4]   n-3 fatty acids and cardiovascular disease [J].
Breslow, Jan L. .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 2006, 83 (06) :1477S-1482S
[5]  
Grundy SM, 2004, CIRCULATION, V109, P433, DOI [10.1161/01.CIR.0000111245.75752.C6, 10.1161/01.CIR.0000112379.88385.67]
[6]   Flaxseed oil during lactation changes milk and body composition in male and female suckling pups rats [J].
Guarda, Deysla Sabino ;
Lisboa, Patricia Cristina ;
de Oliveira, Elaine ;
Nogueira-Neto, Jose Firmino ;
de Moura, Egberto Gaspar ;
Figueiredo, Mariana Sarto .
FOOD AND CHEMICAL TOXICOLOGY, 2014, 69 :69-75
[7]   Perinatal manipulation of α-linolenic acid intake induces epigenetic changes in maternal and offspring livers [J].
Niculescu, Mihai D. ;
Lupu, Daniel S. ;
Craciunescu, Corneliu N. .
FASEB JOURNAL, 2013, 27 (01) :350-358
[8]   Metabolic liver disease of obesity and role of adipose tissue in the pathogenesis of nonalcoholic fatty liver disease [J].
Qureshi, Kamran ;
Abrams, Gary A. .
WORLD JOURNAL OF GASTROENTEROLOGY, 2007, 13 (26) :3540-3553
[9]   Comparative effects of dietary fat types on hepatic enzyme activities related to the synthesis and oxidation of fatty acid and to lipogenesis in rats [J].
Takeuchi, H ;
Nakamoto, T ;
Mori, Y ;
Kawakami, M ;
Mabuchi, H ;
Ohishi, Y ;
Ichikawa, N ;
Koike, A ;
Masuda, K .
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2001, 65 (08) :1748-1754
[10]  
Tripathi V., 2013, INT J PHARM BIOL SCI, V3, P434