Relation of Dietary Glycemic Index and Glycemic Load to Coronary Artery Calcium in Asymptomatic Korean Adults

被引：11

作者：

Choi, Yuni ^{[1
]}

Chang, Yoosoo ^{[1
,2
]}

Ryu, Seungho ^{[1
,2
]}

Cho, Juhee ^{[1
,6
,7
,8
,9
]}

Kim, Mi Kyung ^{[10
]}

Ahn, Younjhin ^{[11
]}

Lee, Jung Eun ^{[12
]}

Sung, Eunju ^{[1
,3
]}

Kim, Boyoung ^{[1
,5
]}

Ahn, Jiin ^{[1
]}

Kim, Chan-Won ^{[1
]}

Rampal, Sanjay ^{[7
,8
,9
,13
]}

Zhao, Di ^{[7
,8
,9
]}

Zhang, Yiyi ^{[7
,8
,9
]}

Pastor-Barriuso, Roberto ^{[14
,15
]}

Lima, Joao A. C. ^{[16
]}

Chung, Bun Chul ^{[1
,4
]}

Shin, Hocheol ^{[1
,3
]}

Guallar, Eliseo ^{[7
,8
,9
]}

机构：

[1] Sungkyunkwan Univ, Sch Med, Kangbuk Samsung Hosp, Ctr Cohort Studies,Total Healthcare Screening Ctr, Seoul, South Korea

[2] Sungkyunkwan Univ, Sch Med, Kangbuk Samsung Hosp, Total Healthcare Screening Ctr,Dept Occupat & Env, Seoul, South Korea

[3] Sungkyunkwan Univ, Sch Med, Kangbuk Samsung Hosp, Total Healthcare Screening Ctr,Dept Family Med, Seoul, South Korea

[4] Sungkyunkwan Univ, Sch Med, Kangbuk Samsung Hosp, Total Healthcare Screening Ctr,Dept Radiol, Seoul, South Korea

[5] Sungkyunkwan Univ, Sch Med, Kangbuk Samsung Hosp, Total Healthcare Screening Ctr,Div Med Nutr, Seoul, South Korea

[6] Sungkyunkwan Univ, SAIHST, Dept Hlth Sci & Technol, Seoul, South Korea

[7] Johns Hopkins Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD USA

[8] Johns Hopkins Bloomberg Sch Publ Hlth, Dept Med, Baltimore, MD USA

[9] Johns Hopkins Bloomberg Sch Publ Hlth, Welch Ctr Prevent Epidemiol & Clin Res, Baltimore, MD USA

[10] Hanyang Univ, Coll Med, Dept Prevent Med, Seoul 133791, South Korea

[11] Natl Inst Hlth, Div Cardiovasc & Rare Dis, Ctr Biomed Sci, Chungbuk, South Korea

[12] Sookmyung Womens Univ, Dept Food & Nutr, Seoul, South Korea

[13] Univ Malaya, Fac Med, Julius Ctr, Dept Social & Prevent Med, Kuala Lumpur, Malaysia

[14] Carlos III Inst Hlth, Natl Ctr Epidemiol, Madrid, Spain

[15] Consortium Biomed Res Epidemiol & Publ Hlth CIBER, Madrid, Spain

[16] Johns Hopkins Univ, Sch Med, Div Cardiol, Baltimore, MD USA

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 2015年 / 116卷 / 04期

关键词：

HEART-DISEASE; RISK-FACTORS; METAANALYSIS; SCORE;

D O I：

10.1016/j.amjcard.2015.05.005

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The relation between glycemic index, glycemic load, and subclinical coronary atherosclerosis is unknown. The aim of the study was to evaluate the associations between energy-adjusted glycemic index, glycemic load, and coronary artery calcium (CAC). This study was cross-sectional analysis of 28,429 asymptomatic Korean men and women (mean age 41.4 years) without a history of diabetes or cardiovascular disease. All participants underwent a health screening examination between March 2011 and April 2013, and dietary intake over the preceding year was estimated using a validated food frequency questionnaire. Cardiac computed tomography was used for CAC scoring. The prevalence of detectable CAC (CAC score >0) was 12.4%. In multivariable-adjusted models, the CAC score ratios (95% confidence intervals) comparing the highest to the lowest quintile of glycemic index and glycemic load were 1.74 (1.08 to 2.81; p trend = 0.03) and 3.04 (1.43 to 6.46; p trend = 0.005), respectively. These associations did not differ by clinical subgroups, including the participants at low cardiovascular risk. In conclusion, these findings suggest that high dietary glycemic index and glycemic load were associated with a greater prevalence and degree of CAC, with glycemic load having a stronger association. (C) 2015 Elsevier Inc. All rights reserved.

引用

页码：520 / 526

页数：7

共 29 条

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