The Unified Multiple System Atrophy Rating Scale: Intrarater reliability

被引：13

作者：

Krismer, Florian ^{[1
]}

Seppi, Klaus ^{[1
]}

Tison, Francois ^{[2
,3
,4
]}

Sampaio, Cristina ^{[5
]}

Zangerl, Anja ^{[1
]}

Peralta, Cecilia ^{[1
,6
]}

Yekhlef, Farid ^{[2
,3
,4
]}

Ghorayeb, Imad ^{[2
,3
,4
]}

Ory-Magne, Fabienne ^{[7
,8
,9
]}

Galitzky, Monique ^{[7
,8
,9
]}

Bozi, Maria ^{[10
]}

Scaravilli, Tommaso ^{[10
,11
]}

Colosimo, Carlo ^{[12
]}

Geser, Felix ^{[1
,13
]}

Rascol, Olivier ^{[7
,8
,9
]}

Poewe, Werner ^{[1
]}

Quinn, Niall P. ^{[10
]}

Wenning, Gregor K. ^{[1
]}

机构：

[1] Innsbruck Med Univ, Div Neurobiol, Dept Neurol & Neurosurg, A-6020 Innsbruck, Austria

[2] Univ Hosp Bordeaux, Dept Neurol, Bordeaux, France

[3] Univ Hosp Bordeaux, French Reference Ctr MSA, Bordeaux, France

[4] Univ Bordeaux 2, CNRS UMR 5293, Inst Neurodegenerat Dis, F-33076 Bordeaux, France

[5] Hop Santa Maria, Ctr Neurosciencias Lisboa, Fac Med Lisboa, Lisbon, Portugal

[6] CEMIC Ctr Med Educ & Clin Res, Dept Neurol, Buenos Aires, DF, Argentina

[7] Univ Hosp, INSERM, CIC 9302, Dept Clin Pharmacol,French Reference Ctr MSA,UMR8, Toulouse, France

[8] Univ Hosp, INSERM, CIC 9302, Dept Neurosci,French Reference Ctr MSA,UMR825, Toulouse, France

[9] Univ Toulouse 3, F-31062 Toulouse, France

[10] Inst Neurol, Sobell Dept Motor Neurosci & Movement Disorders, London WC1N 3BG, England

[11] Osped Angelo, UOC Neurol, Venice, Italy

[12] Univ Roma La Sapienza, Dept Neurol & Psychiat, Rome, Italy

[13] Univ Ulm, Dept Neurol, Ctr Biomed Res, D-7900 Ulm, Germany

来源：

MOVEMENT DISORDERS | 2012年 / 27卷 / 13期

基金：

奥地利科学基金会;

关键词：

multiple system atrophy; UMSARS; rating scale; EMSA-SG; CONSENSUS STATEMENT; DIAGNOSIS; PROGRESSION; AGREEMENT; THERAPY; TRIAL;

D O I：

10.1002/mds.25181

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Background: The Unified Multiple System Atrophy Rating Scale (UMSARS) was developed to provide a surrogate measure of disease progression in multiple system atrophy. In the present study, the intrarater agreement of the motor examination part of the UMSARS was determined. Methods: All patients were first examined face to face, while being video-recorded, by two senior and two junior investigators. The patients' videotaped examinations were reevaluated after 3 months. Intrarater reliability for each item was analyzed by kappa statistics. Results: Overall weighted kappa (?) values were at least substantial or excellent for all UMSARS motor examination items, except for ocular motor dysfunction, which showed only moderate intrarater agreement. Intrarater reliability was comparable between senior and junior raters, with all ? differences being = 0.22. Conclusions: The motor examination part of the UMSARS was found to have satisfactory intrarater reliability in the present cohort. (C) 2012 Movement Disorder Society

引用

页码：1683 / 1685

页数：3

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