Lipase mediated synthesis of sugar fatty acid esters

被引：188

作者：

Gumel, A. M. ^{[1
]}

Annuar, M. S. M. ^{[1
]}

Heidelberg, T. ^{[2
]}

Chisti, Y. ^{[3
]}

机构：

[1] Univ Malaya, Inst Biol Sci, Fac Sci, Kuala Lumpur 50603, Malaysia

[2] Univ Malaya, Dept Chem, Fac Sci, Kuala Lumpur 50603, Malaysia

[3] Massey Univ, Sch Engn, PN 456, Palmerston North, New Zealand

来源：

PROCESS BIOCHEMISTRY | 2011年 / 46卷 / 11期

关键词：

Sugar esters; Esterification; Surfactants; Lipase; Water activity; Nonaqueous media; CANDIDA-ANTARCTICA LIPASE; SOLID-PHASE SYNTHESIS; WATER ACTIVITY CONTROL; DONOR CHAIN-LENGTH; ENZYMATIC-SYNTHESIS; CATALYZED SYNTHESIS; IMMOBILIZED-LIPASE; ORGANIC-SOLVENT; REGIOSELECTIVE SYNTHESIS; SECONDARY ALCOHOLS;

D O I：

10.1016/j.procbio.2011.07.021

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

This review is concerned with lipase catalyzed synthesis of sugar fatty acid esters in water immiscible organic solvents. Sugar esters are widely used nonionic and nontoxic biosurfactants. Certain sugar esters inhibit microbial growth and have other activities. Lipase mediated synthesis has important advantages over conventional chemical synthesis of sugar esters. Lipase catalyzed synthesis is typically carried out in organic solvents having a low water activity to drive the reaction towards synthesis instead of towards ester hydrolysis. The impact of the various reaction conditions on enzymatic synthesis of sugar esters in nonaqueous media is discussed. Considered in particular are the solvent effects; the effects of water activity; the influence of the nature and concentration of the reactants (sugars and fatty acids); the influence of temperature; and the effects associated with the specific nature of the lipase catalyst used. (C) 2011 Elsevier Ltd. All rights reserved.

引用

页码：2079 / 2090

页数：12

共 152 条

[1] Synthesis of esters by immobilized-lipase-catalyzed condensation reaction of sugars and fatty acids in water-miscible organic solvent [J].

Adachi, S ;

Kobayashi, T .

JOURNAL OF BIOSCIENCE AND BIOENGINEERING, 2005, 99 (02) :87-94

[2] ENZYME CATALYZED PREPARATION OF 6-O-ACYLGLUCOPYRANOSIDES [J].

ADELHORST, K ;

BJORKLING, F ;

GODTFREDSEN, SE ;

KIRK, O .

SYNTHESIS-STUTTGART, 1990, (02) :112-115

[3]

Adnani A, 2011, ASIAN J CHEM, V23, P388

[4] SOLVENT DIELECTRIC EFFECTS ON PROTEIN DYNAMICS [J].

AFFLECK, R ;

HAYNES, CA ;

CLARK, DS .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (11) :5167-5170

[5] ENZYMATIC CATALYSIS AND DYNAMICS IN LOW-WATER ENVIRONMENTS [J].

AFFLECK, R ;

XU, ZF ;

SUZAWA, V ;

FOCHT, K ;

CLARK, DS ;

DORDICK, JS .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (03) :1100-1104

[6] Enzymatic synthesis and modification of polymers in nonaqueous solvents [J].

Akkara, JA ;

Ayyagari, MSR ;

Bruno, FF .

TRENDS IN BIOTECHNOLOGY, 1999, 17 (02) :67-73

[7] SYNTHESIS OF ALKYL GLYCOSIDE FATTY-ACID ESTERS - EFFECT OF REACTION PARAMETERS AND THE INCORPORATION OF N-3 POLYUNSATURATED FATTY-ACIDS [J].

AKOH, CC ;

MUTUA, LN .

ENZYME AND MICROBIAL TECHNOLOGY, 1994, 16 (02) :115-119

[8] LIPASE OF PENICILLIUM-CASEICOLUM [J].

ALHIR, S ;

MARKAKIS, P ;

CHANDAN, RC .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 1990, 38 (03) :598-601

[9] A NEW ASSAY FOR LIPASE ACTIVITY IN ORGANIC-SOLVENTS - LIPASE-CATALYZED SYNTHESIS OF OCTYL-LINOLENATE IN A HEXANE MICROAQUEOUS REACTION SYSTEM [J].

AMAYA, CL ;

STUBBS, D ;

MARANGONI, AG .

ENZYME AND MICROBIAL TECHNOLOGY, 1995, 17 (02) :131-135

[10] One biocatalyst - Many applications: The use of Candida antarctica B-lipase in organic synthesis [J].

Anderson, EM ;

Karin, M ;

Kirk, O .

BIOCATALYSIS AND BIOTRANSFORMATION, 1998, 16 (03) :181-204

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