Brca1-deficient pancreatic ductal adenocarcinoma cells are hyper-sensitive to DNA-damaging agents

被引：0
|
作者：
Hirsch, S. [1 ,2 ]
Shakya, R. [2 ]
Szabolcs, M. [2 ]
Hartmann, J-T [1 ]
Ludwig, T. [2 ]
机构：
[1] Univ Klinikum Schleswig Holstein, Kiel, Germany
[2] Columbia Univ, Inst Canc Genet, Dept Pathol & Cell Biol, New York, NY USA
来源：
ONKOLOGIE | 2011年 / 34卷
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：57 / 57
页数：1
相关论文
共 50 条
  • [1] Regulation of BRCA1 and BRCA2 expression in human breast cancer cells by DNA-damaging agents
    Janet L Andres
    Saijun Fan
    Gary J Turkel
    Ji-An Wang
    Nae-Fang Twu
    Ren-Qi Yuan
    Katrin Lamszus
    Itzhak D Goldberg
    Eliot M Rosen
    Oncogene, 1998, 16 : 2229 - 2241
  • [2] Regulation of BRCA1 and BRCA2 expression in human breast cancer cells by DNA-damaging agents
    Andres, JL
    Fan, SJ
    Turkel, GJ
    Wang, JA
    Twu, NF
    Yuan, RQ
    Lamszus, K
    Goldberg, ID
    Rosen, EM
    ONCOGENE, 1998, 16 (17) : 2229 - 2241
  • [3] RAPID DETECTION OF DNA-DAMAGING AGENTS USING REPAIR-DEFICIENT CHO CELLS
    HOY, CA
    SALAZAR, EP
    THOMPSON, LH
    MUTATION RESEARCH, 1984, 130 (05): : 321 - 332
  • [4] Suppression of DNA Polymerase β Activity Is Synthetically Lethal in BRCA1-Deficient Cells
    Yuhas, Shelby C.
    Mishra, Alok
    DeWeese, Theodore L.
    Greenberg, Marc M.
    ACS CHEMICAL BIOLOGY, 2021, 16 (08) : 1339 - 1343
  • [5] USP9X stabilizes BRCA1 and confers resistance to DNA-damaging agents in human cancer cells
    Lu, Qin
    Zhang, Fang-Lin
    Lu, Da-Yun
    Shao, Zhi-Ming
    Li, Da-Qiang
    CANCER MEDICINE, 2019, 8 (15): : 6730 - 6740
  • [6] EXO1 protects BRCA1-deficient cells against toxic DNA lesions
    van de Kooij, Bert
    Schreuder, Anne
    Pavani, Raphael
    Garzero, Veronica
    Uruci, Sidrit
    Wendel, Tiemen J.
    Hoeck, Arne van
    Alonso, Marta San Martin
    Everts, Marieke
    Koerse, Dana
    Callen, Elsa
    Boom, Jasper
    Mei, Hailiang
    Cuppen, Edwin
    Luijsterburg, Martijn S.
    van Vugt, Marcel A. T. M.
    Nussenzweig, Andre
    van Attikum, Haico
    Noordermeer, Sylvie M.
    MOLECULAR CELL, 2024, 84 (04) : 659 - 674.e7
  • [7] Squamous cell carcinoma cells become sensitive to DNA-damaging agents after infection with the adenovirus E1A
    Sanchez, R
    Provencio, M
    Cano, A
    Quintanilla, A
    Cajal, SRY
    EUROPEAN JOURNAL OF CANCER, 1995, 31A : 450 - 450
  • [8] Lack of phenotypic alteration of hmUra-DNA glycosylase-deficient hamster cells exposed to DNA-damaging agents
    Mi, LJ
    Mahl, E
    Chaung, WR
    Boorstein, RJ
    MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 1997, 374 (02) : 287 - 295
  • [9] Patient derived BRCA1-deficient triple-negative breast cancer xenografts develop resistance to DNA damaging agents via genetic and epigenetic mechanisms
    ter Brugge, Petra
    Wesseling, Jelle
    Jonkers, Jos
    van der Burg, Eline
    Kristel, Petra
    Boon, Ute
    Moutinho, Catia
    Esteller, Manel
    Hogervorst, Frans
    Gevensleber, Heidrun
    Turner, Nicholas
    CLINICAL CANCER RESEARCH, 2012, 18 (10)
  • [10] Differences in Sensitivity to DNA-damaging Agents between XRCC4- and Artemis-deficient Human Cells
    Katsube, Takanori
    Mori, Masahiko
    Tsuji, Hideo
    Shiomi, Tadahiro
    Shiomi, Naoko
    Onoda, Makoto
    JOURNAL OF RADIATION RESEARCH, 2011, 52 (04) : 415 - 424
12345