Innate immunity to tropical theileriosis

被引:36
作者
Ahmed, Jabbar S. [1 ]
Glass, Elizabeth J. [2 ,3 ]
Salih, Diaeldin A. [1 ]
Seitzer, Ulrike [1 ]
机构
[1] Res Ctr Borstel, Div Vet Infect Biol & Immunol, D-23845 Borstel, Germany
[2] Roslin Inst, Dept Genet & Genom, Roslin, Midlothian, Scotland
[3] Royal Dick Sch Vet Studies, Roslin Bioctr, Roslin, Midlothian, Scotland
基金
英国惠康基金; 英国生物技术与生命科学研究理事会;
关键词
Theileria annulata; tropical theileriosis; innate immune response; resistant cattle breed;
D O I
10.1177/1753425907087258
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The intracellular protozoan parasite Theileria annulata causes a severe, and often fatal, disease of pure and cross-bred cattle in tropical and subtropical countries. The present review refers to the importance of innate immunity as far as it is known to date in this infectious disease. Specifically, macrophages and the mediators produced by these cells are outlined. In addition, the latest findings concerning cattle breed differences in susceptibility to T. annulata infection in relation to macrophage activation are discussed.
引用
收藏
页码:5 / 12
页数:8
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