Brianodins A-D, briarane-type diterpenoids from soft coral Pachyclavularia sp.

被引：14

作者：

Ishiyama, Haruaki ^{[1
]}

Okubo, Taro ^{[1
]}

Yasuda, Tetsuro ^{[1
]}

Takahashi, Yohei ^{[1
]}

Iguchi, Kazuo ^{[2
]}

Kobayashi, Jun'ichi ^{[1
]}

机构：

[1] Hokkaido Univ, Grad Sch Pharmaceut Sci, Sapporo, Hokkaido 0600812, Japan

[2] Tokyo Univ Pharm & Life Sci, Sch Life Sci, Tokyo 1920392, Japan

来源：

JOURNAL OF NATURAL PRODUCTS | 2008年 / 71卷 / 04期

关键词：

D O I：

10.1021/np070684p

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Four new briarane-type diterpenoids, brianodins A-D (1-4), were isolated from a soft coral, Pachyclavularia sp., and the structures and relative stereochemistry of 1-4 were elucidated on the basis of spectroscopic data. The absolute configurations of 3 and 4 were assigned by the MTPA method. Brianodin A (1) showed a modest cytotoxicity.

引用

页码：633 / 636

页数：4

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