3-(Bromoacetyl)coumarins: unraveling their synthesis, chemistry, and applications

被引：12

作者：

Abdou, Moaz M. ^{[1
]}

Abu-Rayyan, Ahmed ^{[2
]}

Bedir, Ahmed G. ^{[1
]}

Abdel-Fattah, S. ^{[1
]}

Omar, A. M. A. ^{[1
]}

Ahmed, Abdullah A. ^{[3
]}

El-Desoky, El-Sayed, I ^{[4
]}

Ghaith, Eslam A. ^{[4
]}

机构：

[1] Egyptian Petr Res Inst, Cairo 11727, Egypt

[2] Appl Sci Private Univ, Fac Sci, POB 166, Amman 11931, Jordan

[3] Al Azhar Univ, Fac Sci, Dept Chem, Cairo 11884, Egypt

[4] Mansoura Univ, Fac Sci, Dept Chem, Mansoura 35516, Egypt

来源：

RSC ADVANCES | 2021年 / 11卷 / 61期

关键词：

ONE-POT SYNTHESIS; SOLVENT-FREE SYNTHESIS; BIOLOGICAL EVALUATION; COUMARIN-THIAZOLE; MOLECULAR DOCKING; MULTICOMPONENT SYNTHESIS; ANTIMICROBIAL ACTIVITY; GREEN SYNTHESIS; INTRAMOLECULAR AMIDATION; ANTIBACTERIAL ACTIVITY;

D O I：

10.1039/d1ra05574g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

This review emphasizes recent developments in synthetic routes of 3-(bromoacetyl)coumarin derivatives. Also, chemical reactions of 3-(bromoacetyl)coumarins as versatile building blocks in the preparation of critical polyfunctionalized heterocyclic systems and other industrially significant scaffolds are described. Recent advances of 3-(bromoacetyl)coumarins as attractive starting points towards a wide scale of five and six-membered heterocyclic systems such as thiophenes, imidazoles, pyrazoles, thiazoles, triazoles, pyrans, pyridines, thiadiazins as well as fused heterocyclic systems have been reported. Additionally, this review covers a wide range of analytical chemistry, fluorescent sensors, and biological applications of these moieties, covering the literature till May 2021.

引用

页码：38391 / 38433

页数：43

共 183 条

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