Synthesis of 2-[5-(substituted phenyloxy)methyl-1,3,4-thiadiazol-2-ylimino]-5-(substituted benzylidene)-4-thiazolidinones

被引：0

作者：

Wang, Xi-Cun ^{[1
]}

Huang, Guo-Li ^{[1
]}

Quan, Zheng-Jun ^{[1
]}

Lue, Cheng-Wei ^{[1
]}

Yang, Wen-Long ^{[1
]}

机构：

[1] NW Normal Univ, Coll Chem & Chem Engn, Gansu Key Lab Polymer Mat, Lanzhou 730070, Peoples R China

来源：

CHINESE JOURNAL OF ORGANIC CHEMISTRY | 2008年 / 28卷 / 05期

关键词：

2-[5-(substituted phenyloxy)methyl-1,3,4-thiadiazol-2-ylimino]-5-(substituted benzylidene)-4-thiazolidinone; thiazolidinone derivative; synthesis;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of 2-[5-(substituted phenyloxy)methyl-1,3,4-thiadiazol-2-ylimino]-5-(substituted benzylidene)-4-thiazolidinones (4a similar to 4p) were synthesized by quasi-Knoevenagel condensation of 2-[5-(substituted phenyloxy)methyl-1,3,4-thiadiazol-2-yliminol-4-thiazolidinones (3) with substituted benzaldehydes. The intermediates 3 and 2-chloroacetamido-5-(substituted phenyloxy)methyl-1,3,4-thiadiazoles (2) were prepared by using 2-amino-5-(substituted phenyloxy)methyl-1,3,4-thiadiazoles (1) as a starting material. The structures of 4a similar to 4p were confirmed by IR, H-1 NMR spectra and elemental analyses.

引用

页码：870 / 874

页数：5

共 15 条

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