Influence of dietary zinc on lipid peroxidation, protein oxidation and antioxidant defence of juvenile Jian carp (Cyprinus carpio var. Jian)

被引：64
作者：
Feng, L. [1 ,2 ]
Tan, L-N [1 ]
Liu, Y. [1 ,2 ]
Jiang, J. [1 ,2 ]
Jiang, W-D [1 ,2 ]
Hu, K. [1 ,2 ]
Li, S-H [1 ]
Zhou, X-Q [1 ,2 ]
机构：
[1] Sichuan Agr Univ, Inst Anim Nutr, Yaan 625014, Sichuan, Peoples R China
[2] Sichuan Agr Univ, China Minist Educ, Key Lab Anim Disease Resistance Nutr, Yaan 625014, Sichuan, Peoples R China
来源：
AQUACULTURE NUTRITION | 2011年 / 17卷 / 04期
基金：
美国国家科学基金会;
关键词：
antioxidant defence; intestine; Jian carp (Cyprinus carpio var. Jian); lipid peroxidation; protein oxidation; zinc; RAINBOW-TROUT; FISH; GLUTATHIONE; SUPPLEMENTATION; REQUIREMENTS; DEFICIENCY; CAPACITY; CATALASE; ENZYMES; COPPER;
D O I：
10.1111/j.1365-2095.2011.00858.x
中图分类号：
S9 [水产、渔业];
学科分类号：
0908 ;
摘要：
This study was conducted to study the effects of dietary zinc on lipid peroxidation, protein oxidation and antioxidant defence of juvenile Jian carp (Cyprinus carpio var. Jian) by feeding fish with increasing levels of zinc (15.3, 26.9, 40.8, 58.2, 68.9 and 92.5 mg Zn kg(-1)) for 6 weeks. Results indicated that malondialdehyde (MDA) content and protein carbonyls (PC) in serum were the highest in fish fed diet containing 15.3 mg zinc kg(-1) diet (P < 0.05). Serum anti-superoxide anion (ASA), superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), glutathione reductase (GR) activities and glutathione (GSH) content were improved with increasing dietary zinc levels up to 40.8 mg zinc kg(-1) diet (P < 0.05) and levelled off (P > 0.05). Serum antihydroxy radical (AHR), catalase (CAT) and glutathione-S-transferase (GST) activities followed the similar pattern to that observed in ASA. The MDA and PC levels, ASA, AHR, SOD, CAT, GPx, GR, GST activities and GSH content in intestine, hepatosomatic and muscle tissue followed the similar pattern to that observed in serum. The present results indicated that zinc decreased lipid peroxidation and protein oxidation and improved antioxidant defence in fish.
引用
收藏
页码：E875 / E882
页数：8
相关论文
共 43 条
[1]  
AEBI H, 1984, METHOD ENZYMOL, V105, P121
[2]  
[Anonymous], 1984, EPA600679020
[3]  
[Anonymous], 1984, OFF METH AN
[4]  
Bai JX, 2001, BIOL SIGNAL RECEPT, V10, P189
[5]  
BEUTLER E, 1963, J LAB CLIN MED, V61, P882
[6]   Oxidative damage and altered antioxidant enzyme activities in the small intestine of streptozotocin-induced diabetic rats [J].
Bhor, VM ;
Raghuram, N ;
Sivakami, S .
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 2004, 36 (01) :89-97
[7]  
BRADFORD MM, 1976, ANAL BIOCHEM, V72, P248, DOI 10.1016/0003-2697(76)90527-3
[8]  
Cabrini L, 1998, BIOCHEM MOL BIOL INT, V46, P689
[9]   In vivo modulation of immune response and antioxidant defense in Atlantic cod, Gadus morhua following oral administration of oxolinic acid and florfenicol [J].
Caipang, Christopher Marlowe A. ;
Lazado, Carlo C. ;
Brinchmann, Monica F. ;
Berg, Ingvild ;
Kiron, Viswanath .
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY, 2009, 150 (04) :459-464
[10]   VITAMIN-C - THE NONTOXIC, NONRATE-LIMITED, ANTIOXIDANT FREE-RADICAL SCAVENGER [J].
CATHCART, RF .
MEDICAL HYPOTHESES, 1985, 18 (01) :61-77
12345