Naturally Occurring Chromone Glycosides: Sources, Bioactivities, and Spectroscopic Features

被引:27
作者
Amen, Yhiya [1 ,2 ]
Elsbaey, Marwa [2 ]
Othman, Ahmed [1 ,3 ]
Sallam, Mahmoud [3 ]
Shimizu, Kuniyoshi [1 ]
机构
[1] Kyushu Univ, Grad Sch Bioresources & Bioenvironm Sci, Dept Agroenvironm Sci, Fukuoka 8190395, Japan
[2] Mansoura Univ, Fac Pharm, Dept Pharmacognosy, Mansoura 35516, Egypt
[3] Al Azhar Univ, Fac Pharm, Dept Pharmacognosy, Cairo 11371, Egypt
关键词
chromone glycosides; chemical structure; activity; benzo-gamma-pyrone; C-13-NMR data; PLURAMYCIN-LIKE ANTIBIOTICS; ALOE-VERA; CHEMICAL-CONSTITUENTS; 2-(2-PHENYLETHYL)CHROMONE GLYCOSIDE; SECONDARY METABOLITES; ANTIOXIDANT ACTIVITY; C-GLUCOSIDES; FLOWER BUDS; DERIVATIVES; COMPONENTS;
D O I
10.3390/molecules26247646
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Chromone glycosides comprise an important group of secondary metabolites. They are widely distributed in plants and, to a lesser extent, in fungi and bacteria. Significant biological activities, including antiviral, anti-inflammatory, antitumor, antimicrobial, etc., have been discovered for chromone glycosides, suggesting their potential as drug leads. This review compiles 192 naturally occurring chromone glycosides along with their sources, classification, biological activities, and spectroscopic features. Detailed biosynthetic pathways and chemotaxonomic studies are also described. Extensive spectroscopic features for this class of compounds have been thoroughly discussed, and detailed C-13-NMR data of compounds 1-192, have been added, except for those that have no reported C-13-NMR data.
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页数:65
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