Dichloro[(2-dimethylamino)propyldiphenylphosphine]palladium(II) (PdCl2(alaphos)):: An efficient catalyst for cross-coupling of aryl triflates with alkynyl Grignard reagents

被引：43
|
作者：
Kamikawa, T [1 ]
Hayashi, T [1 ]
机构：
[1] Kyoto Univ, Fac Sci, Dept Chem, Kyoto 60601, Japan
来源：
JOURNAL OF ORGANIC CHEMISTRY | 1998年 / 63卷 / 24期
关键词：
D O I：
10.1021/jo981191f
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Dichloro[(2-dimethylamino)propyldiphenylphosphine]palladium (PdCl2(alaphos)) was found to be much more effective as catalyst than other palladium complexes for cross-coupling of aryl triflates with alkynyl Grignard reagents. Reaction of bromoaryl triflates with alkynyl Grignard reagents in the presence of PdCl2(alaphos) catalyst gave high yields of alkynyl arene bromides, which were formed by selective replacement of triflate by alkynyl group.
引用
收藏
页码：8922 / 8925
页数：4
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