Reduction of body weight, body fat mass, and serum leptin levels by addition of new beverage in normal diet of obese subjects

Practical applications Vinegar and garlic are well-known functional foods used in reducing obesity, Hence, a new beverage was developed from dates vinegar and garlic juice in order to reduce obesity. Current investigation focused on 85 obese adults. Participants consumed 500 mL of either beverage or placebo daily into their normal diet for a period of 10 weeks. Body weight, body mass index (BMI), waist circumference, visceral fat area (VFA), serum lipid profile, serum leptin, alanine transaminase (ALT), aspirate transaminase (AST), urea, and creatinine levels were analyzed before and after the treatment. The outcomes indicated that new beverage reduced the body weight (73.96.7 to 69.6 +/- 5.8 kg, p=.002), body fat ratio (29.8 +/- 5.4 to 28.1 +/- 4.2%, p=.004), and serum leptin (36.25 +/- 3.2 to 31.12 +/- 3.7 ng/mL, p=.002), and can therefore play a critical role in preclusion of metabolic syndrome. Dates and garlic, compared with other fruits, are rich source of phenolic compounds and fibers. Researchers have claimed that extracts of dates fruit and garlic are effective in reducing obesity and prevention of metabolic syndrome. Thus, this study was conducted to determine the effects of a new beverage made of dates vinegar and garlic juice on obesity by assessing body weight, BMI, body fat mass, blood pressure, lipid profile, and liver markers. The results of this clinical trial present a latent approach to the avoidance of obesity and provide a possible source of phenolic compounds. This new beverage is suggested as a dietary supplement for the prevention of obesity and metabolic syndrome.