A prospective randomized comparison of diagnostic efficacy between transperineal and transrectal 12-core prostate biopsy

被引:93
作者
Takenaka, A. [1 ]
Hara, R. [2 ]
Ishimura, T. [1 ]
Fujii, T. [2 ]
Jo, Y. [2 ]
Nagai, A. [2 ]
Fujisawa, M. [1 ]
机构
[1] Kobe Univ, Grad Sch Med, Dept Organ Therapeut, Div Urol,Chuo Ku, Kobe, Hyogo 6500017, Japan
[2] Kawasaki Med Sch, Dept Urol, Kurashiki, Okayama, Japan
关键词
biopsy; transrectal approach; transperineal approach;
D O I
10.1038/sj.pcan.4500985
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The aim of this study is to elucidate the diagnostic efficacy between transperineal and transrectal 12-core prostate biopsy for prostate cancer. We prospectively randomized 200 consecutive men into two groups to undergo systematic prostate biopsy. Overall positivity for cancer was similar (47% by transperineal and 53% by transrectal; P = 0.480). However, in case with 'gray zone' PSA (from 4.1 to 10.0 ng/ml), significantly more cores were positive when approach was transperineal, especially among transition zone cores. Therefore, urologist preferences are sufficient for choosing an approach, except for a possible small advantage of transperineal biopsy when PSA is in gray zone.
引用
收藏
页码:134 / 138
页数:5
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