Cancer and fertility preservation: fertility preservation in breast cancer patients

被引：35

作者：

Maltaris, Theodoros ^{[1
,2
]}

Weigel, Michael ^{[2
]}

Mueller, Andreas ^{[3
]}

Schmidt, Marcus ^{[1
]}

Seufert, Rudolf ^{[1
]}

Fischl, Franz ^{[1
]}

Koelbl, Heinz ^{[1
]}

Dittrich, Ralf ^{[3
]}

机构：

[1] Johannes Gutenberg Univ Mainz, Mainz Univ Hosp, Dept Obstet & Gynecol, D-55124 Mainz, Germany

[2] Leopoldina Hosp, Dept Obstet & Gynecol, D-97421 Schweinfurt, Germany

[3] Univ Erlangen Nurnberg, Erlangen Univ Hosp, Dept Obstet & Gynecol, D-91054 Erlangen, Germany

来源：

BREAST CANCER RESEARCH | 2008年 / 10卷 / 02期

关键词：

D O I：

10.1186/bcr1991

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Aggressive chemotherapy has improved the life expectancy for reproductive-age women with breast cancer, but it often causes infertility or premature ovarian failure due to destruction of the ovarian reserve. Many questions concerning fertility preservation in breast cancer patients remain unanswered - for example, whether fertility preservation methods interfere with chemotherapy, and whether subsequent pregnancy has negative effects on the prognosis. Fertility preservation is a critical factor in decision-making for younger breast cancer patients, however, and clinicians should address this. The present article reviews the incidence of chemotherapy-induced amenorrhea, and discusses fertility-preservation options and the prognosis for patients who become pregnant after breast cancer.

引用

页数：11

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