Idiopathic pulmonary fibrosis: Treatment update

被引:18
作者
O'Connell, Oisin J. [1 ]
Kennedy, Marcus P. [1 ]
Henry, Michael T. [1 ]
机构
[1] Natl Univ Ireland Univ Coll Cork, Dept Resp Med, Cork, Ireland
关键词
antifibrotic; idiopathic pulmonary fibrosis; patient management; treatment; PLACEBO-CONTROLLED TRIAL; ACID GASTROESOPHAGEAL-REFLUX; CELL LUNG-CANCER; INTERFERON GAMMA-1B; FACTOR EXPRESSION; PROGNOSTIC VALUE; HIGH PREVALENCE; DOUBLE-BLIND; PIRFENIDONE; HYPERTENSION;
D O I
10.1007/s12325-011-0066-5
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Idiopathic pulmonary fibrosis (IPF) is the most common of the idiopathic interstitial pneumonias. Despite multiple recent clinical trials, there is no strong evidence supporting a survival advantage for any agent in the management of patients with IPF. The limited effectiveness of current treatment regimes has led to a search for novel therapies including antifibrotic strategies. This article reviews the evidence supporting the treatments currently used in the management of IPF.
引用
收藏
页码:986 / 999
页数:14
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