共 62 条
Idiopathic pulmonary fibrosis: Treatment update
被引:18
作者:
O'Connell, Oisin J.
[1
]
Kennedy, Marcus P.
[1
]
Henry, Michael T.
[1
]
机构:
[1] Natl Univ Ireland Univ Coll Cork, Dept Resp Med, Cork, Ireland
关键词:
antifibrotic;
idiopathic pulmonary fibrosis;
patient management;
treatment;
PLACEBO-CONTROLLED TRIAL;
ACID GASTROESOPHAGEAL-REFLUX;
CELL LUNG-CANCER;
INTERFERON GAMMA-1B;
FACTOR EXPRESSION;
PROGNOSTIC VALUE;
HIGH PREVALENCE;
DOUBLE-BLIND;
PIRFENIDONE;
HYPERTENSION;
D O I:
10.1007/s12325-011-0066-5
中图分类号:
R-3 [医学研究方法];
R3 [基础医学];
学科分类号:
1001 ;
摘要:
Idiopathic pulmonary fibrosis (IPF) is the most common of the idiopathic interstitial pneumonias. Despite multiple recent clinical trials, there is no strong evidence supporting a survival advantage for any agent in the management of patients with IPF. The limited effectiveness of current treatment regimes has led to a search for novel therapies including antifibrotic strategies. This article reviews the evidence supporting the treatments currently used in the management of IPF.
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页码:986 / 999
页数:14
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