Mitsunobu Reaction of 1,2,3-NH-Triazoles: A Regio- and Stereoselective Approach to Functionalized Triazole Derivatives

被引：44

作者：

Yan, Wuming ^{[1
]}

Liao, Tao ^{[1
]}

Tuguldur, Odbadrakh ^{[1
]}

Zhong, Cheng ^{[1
]}

Petersen, Jeffrey L. ^{[1
]}

Shi, Xiaodong ^{[1
]}

机构：

[1] W Virginia Univ, C Eugene Bennett Dept Chem, Morgantown, WV 26506 USA

来源：

CHEMISTRY-AN ASIAN JOURNAL | 2011年 / 6卷 / 10期

基金：

美国国家科学基金会;

关键词：

1,2,3-triazoles; click chemistry; enantioselectivity; Mitsunobu reaction; regioselectivity; AZIDE-ALKYNE CYCLOADDITION; CLICK CHEMISTRY; REGIOSELECTIVE SYNTHESIS; EFFICIENT SYNTHESIS; DIRECT ARYLATIONS; COMPLEXES; 1,2,3-TRIAZOLES; LIGANDS; ACTIVATION; COORDINATION;

D O I：

10.1002/asia.201100357

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The Mitsunobu reaction was used in the preparation of chiral triazole derivatives. The reactions gave good to excellent yields with large substrate scope. Complete stereochemistry inversion was obtained, making this strategy one practical approach for the synthesis of enantiomeric enriched triazole analogous. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：2720 / 2724

页数：5

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