Advances in the application of comprehensive two-dimensional gas chromatography in metabolomics

被引：92

作者：

Keppler, Emily A. Higgins ^{[1
]}

Jenkins, Carrie L. ^{[1
]}

Davis, Trenton J. ^{[1
]}

Bean, Heather D. ^{[1
]}

机构：

[1] Arizona State Univ, Sch Life Sci, Tempe, AZ 85287 USA

来源：

TRAC-TRENDS IN ANALYTICAL CHEMISTRY | 2018年 / 109卷

关键词：

Animal models; Biospecimens; Biotransformation; Comprehensive two-dimensional gas chromatography (GC x GC); Data reporting; In vitro analyses; Metabolomics; Multitrophic interactions; Sampling; FLIGHT MASS-SPECTROMETRY; SOLID-PHASE MICROEXTRACTION; MYCOBACTERIUM-TUBERCULOSIS; CHRYSOLINA-HERBACEA; EXHALED BREATH; GC-MS; ALIGNMENT; POTENTIALITIES; OPTIMIZATION; METABOLITES;

D O I：

10.1016/j.trac.2018.10.015

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Due to excellent separation capacity for complex mixtures of chemicals, comprehensive twodimensional gas chromatography (GC x GC) is being utilized with increasing frequency for metabolomics analyses. This review describes recent advances in GC x GC method development for metabolomics, organismal sampling techniques compatible with GC x GC, metabolomic discoveries made using GC x GC, and recommendations and best practices for collecting and reporting GC x GC metabolomics data. (C) 2018 The Authors.Published by Elsevier B.V.

引用

页码：275 / 286

页数：12

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