Direct synthesis of 2-substituted benzonitrilesviaalkylcyanation of arynes withN,N-disubstituted aminomalononitriles

被引：9

作者：

Bao, Wen ^{[1
,2
]}

Gao, Zhu-Peng ^{[1
,2
]}

Jin, Ping ^{[1
,2
]}

Xue, Cao-Gen ^{[1
,2
]}

Liang, Huan ^{[1
,2
]}

Lei, Ling-Sheng ^{[1
,2
]}

Xu, Xue-Tao ^{[3
]}

Zhang, Kun ^{[3
]}

Wang, Shao-Hua ^{[1
,2
,3
]}

机构：

[1] Lanzhou Univ, Sch Pharm, Lanzhou 730000, Peoples R China

[2] Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China

[3] Wuyi Univ, Sch Biotechnol & Hlth Sci, Jiangmen 529020, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2020年 / 56卷 / 55期

基金：

中国国家自然科学基金;

关键词：

REGIOSPECIFIC SYNTHESIS; ALPHA-LITHIONITRILES; TANDEM ADDITION; INSERTION; CYANATION; REARRANGEMENT; CONSTRUCTION; DISCOVERY; BENZENES; ROUTE;

D O I：

10.1039/d0cc01591a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An efficient alkylcyanation ofin situgenerated arynes byN,N-disubstituted aminomalononitriles is described, enabling the direct synthesis of 2-substituted benzonitriles.

引用

页码：7641 / 7644

页数：4

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