Genetic variations at four tetrameric tandem repeat loci in Korean population

被引：0
作者：
Park, SJ
Lee, WG
Lee, SW
Kim, SH
Koo, BS
Budowle, B
Rho, HM
机构：
[1] SEOUL NATL UNIV, DEPT MOL BIOL, SEOUL 151742, SOUTH KOREA
[2] SEOUL NATL UNIV, RES CTR CELL DIFFERENTIAT, SEOUL 151742, SOUTH KOREA
[3] INJE UNIV, DEPT BIOL, KIMHAE 621749, SOUTH KOREA
[4] SUPREME PUBL PROSECUTORS OFF, LAB DNA ANAL & CRIMINALIST INSTRUCT DIV, SEOUL 137756, SOUTH KOREA
[5] FED BUR INVEST ACAD, CTR FORENS SCI RES & TRAINING, QUANTICO, VA 22135 USA
来源：
JOURNAL OF FORENSIC SCIENCES | 1997年 / 42卷 / 01期
关键词：
forensic science; DNA typing; FES/FPS; FOLP23; GABRB15; CYAR04; short tandem repeat; Hardy-Weinberg equilibrium; population genetics; Korea;
D O I：
暂无
中图分类号：
DF [法律]; D9 [法律]; R [医药、卫生];
学科分类号：
0301 ; 10 ;
摘要：
Allele and genotype frequencies for four tetrameric short tandem repeat (STR) loci, HumFES/FPS, HumFOLP23, HumGABRB15, and HumCYAR04, have been determined by polymerase chain reaction (PCR) amplification and subsequent polyacrylamide gel electrophoresis from approximately 200 genetically unrelated Koreans. This method allows a single base pair resolution and rapid typing with silver staining. The allele and genotype distributions satisfy Hardy-Weinberg expectation. Also, these STR loci have proven to be useful for forensic analyses and paternity tests in which the variable number of tandem repeat (VNTR) loci have some limitations.
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页码：125 / 129
页数：5
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