Alternative splicing in plants

被引：25

作者：

Simpson, Craig G. ^{[1
]}

Lewandowska, Dominika ^{[1
]}

Fuller, John ^{[1
]}

Maronova, Monika ^{[2
]}

Kalyna, Maria ^{[2
]}

Davidson, Diane ^{[1
]}

McNicol, Jim

Raczynska, Dorota ^{[3
]}

Jarmolowski, Artur ^{[3
]}

Barta, Andrea ^{[2
]}

Brown, John W. S. ^{[1
,4
]}

机构：

[1] Scottish Crop Res Inst, Genet Programme, Dundee DD2 5DA, Scotland

[2] Med Univ Vienna, Max F Perutz Labs, A-1030 Vienna, Austria

[3] Adam Mickiewicz Univ, Inst Mol Biol & Biotechnol, Dept Gene Express, PL-60371 Poznan, Poland

[4] Univ Dundee, SCRI, Plant Sci Div, Dundee DD2 5DA, Scotland

来源：

BIOCHEMICAL SOCIETY TRANSACTIONS | 2008年 / 36卷

关键词：

alternative splicing; Arabidopsis; precursor mRNA; splicing factor; transcription factor;

D O I：

10.1042/BST0360508

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The impact of AS (alternative splicing) is well-recognized in animal systems as a key regulator of gene expression and proteome complexity. In plants, AS is of growing importance as more genes are found to undergo AS, but relatively little is known about the factors regulating AS or the consequences of AS on mRNA levels and protein function. We have established an accurate and reproducible RT (reverse transcription)-PCR system to analyse AS in multiple genes. initial studies have identified new AS events confirming that current values for the frequency of AS in plants are likely to be underestimates.

引用

页码：508 / 510

页数：3

共 15 条

[1] Mechanisms of alternative pre-messenger RNA splicing [J].

Black, DL .

ANNUAL REVIEW OF BIOCHEMISTRY, 2003, 72 :291-336

[2] Alternative splicing: New insights from global analyses [J].

Blencowe, Benjamin J. .

CELL, 2006, 126 (01) :37-47

[3] Plant gene and alternatively spliced variant annotator. A plant genome annotation pipeline for rice gene and alternatively spliced variant identification with cross-species expressed sequence tag conservation from seven plant species [J].

Chen, Feng-Chi ;

Wang, Sheng-Shun ;

Chaw, Shu-Miaw ;

Huang, Yao-Ting ;

Chuang, Trees-Juen .

PLANT PHYSIOLOGY, 2007, 143 (03) :1086-1095

[4] Genome-wide analysis of alternative pre-mRNA splicing in Arabidopsis thaliana based on full-length cDNA sequences [J].

Iida, K ;

Seki, M ;

Sakurai, T ;

Satou, M ;

Akiyama, K ;

Toyoda, T ;

Konagaya, A ;

Shinozaki, K .

NUCLEIC ACIDS RESEARCH, 2004, 32 (17) :5096-5103

[5] Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays [J].

Johnson, JM ;

Castle, J ;

Garrett-Engele, P ;

Kan, ZY ;

Loerch, PM ;

Armour, CD ;

Santos, R ;

Schadt, EE ;

Stoughton, R ;

Shoemaker, DD .

SCIENCE, 2003, 302 (5653) :2141-2144

[6] Ectopic expression of atRSZ33 reveals its function in splicing and causes pleiotropic changes in development [J].

Kalyna, M ;

Lopato, S ;

Barta, A .

MOLECULAR BIOLOGY OF THE CELL, 2003, 14 (09) :3565-3577

[7] Evidence for the widespread coupling of alternative splicing and nonsense-mediated mRNA decay in humans [J].

Lewis, BP ;

Green, RE ;

Brenner, SE .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (01) :189-192

[8] atSRp30, one of two SF2/ASF-like proteins from Arabidopsis thaliana, regulates splicing of specific plant genes [J].

Lopato, S ;

Kalyna, M ;

Dorner, S ;

Kobayashi, R ;

Krainer, AR ;

Barta, A .

GENES & DEVELOPMENT, 1999, 13 (08) :987-1001

[9] Nonsense-mediated mRNA decay: Splicing, translation and mRNP dynamics [J].

Maquat, LE .

NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2004, 5 (02) :89-99

[10] Global analysis of mRNA splicing [J].

Moore, Michael J. ;

Silver, Pamela A. .

RNA, 2008, 14 (02) :197-203

← 1 2 →