Pericytes and ocular diseases

被引：66

作者：

Motiejunaite, Ruta ^{[1
]}

Kazauskas, Andrius ^{[1
,2
]}

机构：

[1] Harvard Univ, Sch Med, Schepens Eye Res Inst, Boston, MA 02114 USA

[2] Vilnius State Univ, Dept Biochem & Biophys, Vilnius, Lithuania

来源：

EXPERIMENTAL EYE RESEARCH | 2008年 / 86卷 / 02期

关键词：

pericyte; ocular diseases; diabetic retinopathy; retinopathy of prematurity; angiogenesis;

D O I：

10.1016/j.exer.2007.10.013

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Pericytes are vascular mural cells which play multiple roles in angiogenesis and maintenance of blood vessel morphology and stability. In this review, we analyze recent data on the participation of pericytes in the pathogenesis of proliferative and non-proliferative diabetic retinopathy, as well as an emerging role in other angiogenic ocular diseases such as retinopathy of prematurity. Ways to exploit pericytes as targets for treatment of ocular diseases are discussed. (c) 2007 Published by Elsevier Ltd.

引用

页码：171 / 177

页数：7

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