BCMA CAR T-cell therapy arrives for multiple myeloma: a reality

被引：9
作者：
Cho, Shih-Feng [1 ,2 ,3 ,4 ]
Anderson, Kenneth C. [1 ,2 ]
Tai, Yu-Tzu [1 ,2 ]
机构：
[1] Harvard Med Sch, Dana Farber Canc Inst, LeBow Inst Myeloma Therapeut, Boston, MA USA
[2] Harvard Med Sch, Dana Farber Canc Inst, Jerome Lipper Multiple Myeloma Ctr, Boston, MA USA
[3] Kaohsiung Med Univ, Kaohsiung Med Univ Hosp, Dept Internal Med, Div Hematol & Oncol, Kaohsiung, Taiwan
[4] Kaohsiung Med Univ, Coll Med, Fac Med, Kaohsiung, Taiwan
来源：
ANNALS OF TRANSLATIONAL MEDICINE | 2018年 / 6卷
基金：
美国国家卫生研究院;
关键词：
MATURATION ANTIGEN; REMISSIONS; RECEPTORS;
D O I：
10.21037/atm.2018.11.14
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页数：5
相关论文
共 25 条
[1]   T cells expressing an anti-B-cell maturation antigen chimeric antigen receptor cause remissions of multiple myeloma [J].
Ali, Syed Abbas ;
Shi, Victoria ;
Maric, Irina ;
Wang, Michael ;
Stroncek, David F. ;
Rose, Jeremy J. ;
Brudno, Jennifer N. ;
Stetler-Stevenson, Maryalice ;
Feldman, Steven A. ;
Hansen, Brenna G. ;
Fellowes, Vicki S. ;
Hakim, Frances T. ;
Gress, Ronald E. ;
Kochenderfer, James N. .
BLOOD, 2016, 128 (13) :1688-1700
[2]   Osteoclasts promote immune suppressive microenvironment in multiple myeloma: therapeutic implication [J].
An, Gang ;
Acharya, Chirag ;
Feng, Xiaoyan ;
Wen, Kenneth ;
Zhong, Mike ;
Zhang, Li ;
Munshi, Nikhil C. ;
Qiu, Lugui ;
Tai, Yu-Tzu ;
Anderson, Kenneth C. .
BLOOD, 2016, 128 (12) :1590-1603
[3]  
[Anonymous], BLOOD
[4]  
Auclair D, 2017, BLOOD, V130
[5]   Safety and persistence of adoptively transferred autologous CD19-targeted T cells in patients with relapsed or chemotherapy refractory B-cell leukemias [J].
Brentjens, Renier J. ;
Riviere, Isabelle ;
Park, Jae H. ;
Davila, Marco L. ;
Wang, Xiuyan ;
Stefanski, Jolanta ;
Taylor, Clare ;
Yeh, Raymond ;
Bartido, Shirley ;
Borquez-Ojeda, Oriana ;
Olszewska, Malgorzata ;
Bernal, Yvette ;
Pegram, Hollie ;
Przybylowski, Mark ;
Hollyman, Daniel ;
Usachenko, Yelena ;
Pirraglia, Domenick ;
Hosey, James ;
Santos, Elmer ;
Halton, Elizabeth ;
Maslak, Peter ;
Scheinberg, David ;
Jurcic, Joseph ;
Heaney, Mark ;
Heller, Glenn ;
Frattini, Mark ;
Sadelain, Michel .
BLOOD, 2011, 118 (18) :4817-4828
[6]   T Cells Genetically Modified to Express an Anti-B-Cell Maturation Antigen Chimeric Antigen Receptor Cause Remissions of Poor-Prognosis Relapsed Multiple Myeloma [J].
Brudno, Jennifer N. ;
Maric, Irina ;
Hartman, Steven D. ;
Rose, Jeremy J. ;
Wang, Michael ;
Lam, Norris ;
Stetler-Stevenson, Maryalice ;
Salem, Dalia ;
Yuan, Constance ;
Pavletic, Steven ;
Kanakry, Jennifer A. ;
Ali, Syed Abbas ;
Mikkilineni, Lekha ;
Feldman, Steven A. ;
Stroncek, David F. ;
Hansen, Brenna G. ;
Lawrence, Judith ;
Patel, Rashmika ;
Hakim, Frances ;
Gress, Ronald E. ;
Kochenderfer, James N. .
JOURNAL OF CLINICAL ONCOLOGY, 2018, 36 (22) :2267-+
[7]   B-cell Maturation Antigen Is a Promising Target for Adoptive T-cell Therapy of Multiple Myeloma [J].
Carpenter, Robert O. ;
Evbuomwan, Moses O. ;
Pittaluga, Stefania ;
Rose, Jeremy J. ;
Raffeld, Mark ;
Yang, Shicheng ;
Gress, Ronald E. ;
Hakim, Frances T. ;
Kochenderfer, James N. .
CLINICAL CANCER RESEARCH, 2013, 19 (08) :2048-2060
[8]   Targeting B Cell Maturation Antigen (BCMA) in Multiple Myeloma: Potential Uses of BCMA-Based Immunotherapy [J].
Cho, Shih-Feng ;
Anderson, Kenneth C. ;
Tai, Yu-Tzu .
FRONTIERS IN IMMUNOLOGY, 2018, 9
[9]   Efficacy and Toxicity Management of 19-28z CAR T Cell Therapy in B Cell Acute Lymphoblastic Leukemia [J].
Davila, Marco L. ;
Riviere, Isabelle ;
Wang, Xiuyan ;
Bartido, Shirley ;
Park, Jae ;
Curran, Kevin ;
Chung, Stephen S. ;
Stefanski, Jolanta ;
Borquez-Ojeda, Oriana ;
Olszewska, Malgorzata ;
Qu, Jinrong ;
Wasielewska, Teresa ;
He, Qing ;
Fink, Mitsu ;
Shinglot, Himaly ;
Youssif, Maher ;
Satter, Mark ;
Wang, Yongzeng ;
Hosey, James ;
Quintanilla, Hilda ;
Halton, Elizabeth ;
Bernal, Yvette ;
Bouhassira, Diana C. G. ;
Arcila, Maria E. ;
Gonen, Mithat ;
Roboz, Gail J. ;
Maslak, Peter ;
Douer, Dan ;
Frattini, Mark G. ;
Giralt, Sergio ;
Sadelain, Michel ;
Brentjens, Renier .
SCIENCE TRANSLATIONAL MEDICINE, 2014, 6 (224)
[10]   CAR-Ts move beyond B-cell cancers to myeloma [J].
Dolgin, Elie .
NATURE BIOTECHNOLOGY, 2017, 35 (07) :599-601
123