Minocycline hyperpigmentation isolated to the subcutaneous fat

被引：11
作者：
Rahman, Z
Lazova, R
Antaya, RJ
机构：
[1] Yale Univ, Sch Med, Dept Dermatol, New Haven, CT 06520 USA
[2] Yale Univ, Sch Med, Dept Pediat, New Haven, CT 06520 USA
[3] Yale Univ, Sch Med, Dept Internal Med, New Haven, CT 06520 USA
来源：
JOURNAL OF CUTANEOUS PATHOLOGY | 2005年 / 32卷 / 07期
关键词：
D O I：
10.1111/j.0303-6987.2005.00369.x
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
We present a 15-year-old girl with bilateral lower extremity discoloration of one-year duration while taking minocycline for acne vulgaris. The clinical characteristics best supported type II minocycline hyperpigmentation, but the histology revealed that the pigmentation was solely limited to the subcutaneous adipose tissue, completely sparing the dermis. Special stain for iron was negative. This is the first case to our knowledge with pigment exclusively located in the subcutaneous fat and with the unusual finding of a negative stain for iron.
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页码：516 / 519
页数：4
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