In situ synthesis of porous silica nanoparticles for covalent immobilization of enzymes

被引：41
作者：
Yang, Xiaowei [1 ]
Cai, Zhengwei [1 ]
Ye, Zhangmei [1 ]
Chen, Sheng [1 ]
Yang, Yu [1 ]
Wang, Haifang [1 ]
Liu, Yuanfang [1 ,2 ]
Cao, Aoneng [1 ]
机构：
[1] Shanghai Univ, Inst Nanochem & Nanobiol, Shanghai 200444, Peoples R China
[2] Peking Univ, Beijing Natl Lab Mol Sci, Coll Chem & Mol Engn, Beijing 100871, Peoples R China
来源：
NANOSCALE | 2012年 / 4卷 / 02期
关键词：
SOL-GEL PROCESS; MESOPOROUS SILICA; ENCAPSULATION; PROTEIN; CATALASE; MICROEMULSION; BIOCATALYSIS; BIOLOGICALS; LYSOZYME; POLYMERS;
D O I：
10.1039/c1nr11153a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A simple method is used to covalently encapsulate enzymes in silica nanoparticles. The encapsulation is highlighted by the high enzyme loading and porous channels that provide efficient diffusion for small substrate and product molecules while preventing protease degradation.
引用
收藏
页码：414 / 416
页数：3
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